The PPP1R15 Family of eIF2-alpha Phosphatase Targeting Subunits (GADD34 and CReP)
The vertebrate PPP1R15 family consists of the proteins GADD34 (growth arrest and DNA damage-inducible protein 34, the product of the PPP1R15A gene) and CReP (constitutive repressor of eIF2α phosphorylation, the product of the PPP1R15B gene), both of which function as targeting/regulatory subunits fo...
Main Authors: | Danielle Hicks, Krithika Giresh, Lisa A. Wrischnik, Douglas C. Weiser |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/24/17321 |
Similar Items
-
Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation
by: Joseph E Chambers, et al.
Published: (2015-03-01) -
Substrate recognition determinants of human eIF2α phosphatases
by: George Hodgson, et al.
Published: (2021-12-01) -
The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (<i>ppp1r14</i>) Family of Protein Phosphatase 1 Inhibitors in Teleosts
by: Irene Lang, et al.
Published: (2020-08-01) -
Novel Variants of PPP2R1A in Catalytic Subunit Binding Domain and Genotype–Phenotype Analysis in Neurodevelopmentally Delayed Patients
by: Yanyan Qian, et al.
Published: (2023-09-01) -
PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis
by: Jason A. Kirkbride, et al.
Published: (2023-12-01)