Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells

Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells

MicroRNAs are key post-transcriptional gene regulators often displaying aberrant expression patterns in cancer. As microRNAs are promising disease-associated biomarkers and modulators of responsiveness to anti-cancer therapies, a solid understanding of their targetome is crucial. Despite enormous re...

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Bibliographic Details
Main Authors: Ines Kozar, Demetra Philippidou, Christiane Margue, Lauren A. Gay, Rolf Renne, Stephanie Kreis
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
melanoma
microRNA
qCLASH
targetome
BRAF
Online Access:https://www.mdpi.com/2072-6694/13/5/1096

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