Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations
Abstract Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the 2011 European Respiratory Society guid...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2017-10-01
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| Series: | Multidisciplinary Respiratory Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40248-017-0106-3 |
| _version_ | 1797282477155287040 |
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| author | Marco Mantero Paolo Tarsia Andrea Gramegna Sonia Henchi Nicolò Vanoni Marta Di Pasquale |
| author_facet | Marco Mantero Paolo Tarsia Andrea Gramegna Sonia Henchi Nicolò Vanoni Marta Di Pasquale |
| author_sort | Marco Mantero |
| collection | DOAJ |
| description | Abstract Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the 2011 European Respiratory Society guidelines, and the 2009 British Thoracic Society guidelines, updated by the NICE in 2015. Despite the validity of current guidelines in improving prognosis and management of patients with community-acquired pneumonia, not all recommendations have high levels of evidence and there are still some controversial issues. In particular, there are some areas of low evidence such as the efficacy of an antibiotic molecule or scheme in patients with same risk factors; duration of antibiotic treatment, supportive therapy for acute respiratory failure and immunomodulation molecules. This review will summarize the main recommendations with high level of evidence and discuss the recommendations with lower evidence, analyzing the studies published after the guidelines’ release. |
| first_indexed | 2024-03-07T17:13:38Z |
| format | Article |
| id | doaj.art-2f5e19fa6e4c4a0b9e4c402d77a37e35 |
| institution | Directory Open Access Journal |
| issn | 2049-6958 |
| language | English |
| last_indexed | 2024-03-07T17:13:38Z |
| publishDate | 2017-10-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Multidisciplinary Respiratory Medicine |
| spelling | doaj.art-2f5e19fa6e4c4a0b9e4c402d77a37e352024-03-02T23:57:17ZengPAGEPress PublicationsMultidisciplinary Respiratory Medicine2049-69582017-10-011211910.1186/s40248-017-0106-3Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendationsMarco Mantero0Paolo Tarsia1Andrea Gramegna2Sonia Henchi3Nicolò Vanoni4Marta Di Pasquale5Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore PoliclinicoAbstract Community-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the 2011 European Respiratory Society guidelines, and the 2009 British Thoracic Society guidelines, updated by the NICE in 2015. Despite the validity of current guidelines in improving prognosis and management of patients with community-acquired pneumonia, not all recommendations have high levels of evidence and there are still some controversial issues. In particular, there are some areas of low evidence such as the efficacy of an antibiotic molecule or scheme in patients with same risk factors; duration of antibiotic treatment, supportive therapy for acute respiratory failure and immunomodulation molecules. This review will summarize the main recommendations with high level of evidence and discuss the recommendations with lower evidence, analyzing the studies published after the guidelines’ release.http://link.springer.com/article/10.1186/s40248-017-0106-3Acute respiratory failureAntibiotic therapyCommunity acquired pneumoniaDuration of therapyInflammatory response |
| spellingShingle | Marco Mantero Paolo Tarsia Andrea Gramegna Sonia Henchi Nicolò Vanoni Marta Di Pasquale Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations Multidisciplinary Respiratory Medicine Acute respiratory failure Antibiotic therapy Community acquired pneumonia Duration of therapy Inflammatory response |
| title | Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations |
| title_full | Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations |
| title_fullStr | Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations |
| title_full_unstemmed | Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations |
| title_short | Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations |
| title_sort | antibiotic therapy supportive treatment and management of immunomodulation inflammation response in community acquired pneumonia review of recommendations |
| topic | Acute respiratory failure Antibiotic therapy Community acquired pneumonia Duration of therapy Inflammatory response |
| url | http://link.springer.com/article/10.1186/s40248-017-0106-3 |
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