Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation

Glioblastoma multiforme (GBM) is the most frequent and most aggressive brain tumor in adults. The dismal prognosis is due to postsurgery recurrences arising from escaped invasive tumor cells. The signaling pathways activated in invasive cells are under investigation, and models are currently designe...

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Main Authors: Jennifer R. Molina, Yuho Hayashi, Clifton Stephens, Maria-Magdalena Georgescu
格式: Article
語言:English
出版: Elsevier 2010-06-01
叢編:Neoplasia: An International Journal for Oncology Research
在線閱讀:http://www.sciencedirect.com/science/article/pii/S147655861080003X