Tackling the SARS-CoV-2 main protease using hybrid derivatives of 1,5-disubstituted tetrazole-1,2,3-triazoles: an in silico assay

Tackling the SARS-CoV-2 main protease using hybrid derivatives of 1,5-disubstituted tetrazole-1,2,3-triazoles: an in silico assay

In regard to the actual public health global emergency and, based on the state of the art about the ways to inhibit the SARS-CoV-2 treating the COVID19, a family of 1,5-disubstituted tetrazole-1,2,3-triazoles, previously synthesized, have been evaluated through in silico assays against the main prot...

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Bibliographic Details
Main Authors:	Carlos J. Cortés-García, Luis Chacón-García, Jorge Emmanuel Mejía-Benavides, Erik Díaz-Cervantes
Format:	Article
Language:	English
Published:	PeerJ Inc. 2020-06-01
Series:	PeerJ Physical Chemistry
Subjects:	SARS-CoV-2 COVID19 1,5-disubstituted-tetrazole-1,2,3-triazoles CoV-2-MPro Docking-assays Pharmacophore-model
Online Access:	https://peerj.com/articles/pchem-10.pdf

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