ELK3 modulates the antitumor efficacy of natural killer cells against triple negative breast cancer by regulating mitochondrial dynamics
Background Triple negative breast cancer (TNBC) is the most lethal subtype of breast cancer due to its aggressive behavior and frequent development of resistance to chemotherapy. Although natural killer (NK) cell-based immunotherapy is a promising strategy for overcoming barriers to cancer treatment...
Main Authors: | Jin-Ho Choi, Joo Dong Park, Kwang-Soo Kim, Seung Hee Choi, Gae Hoon Jo, Si-Won Park, Eun-Su Ko, Minwook Lee, Dae-Keum Lee, Hye Jung Jang, Sohyun Hwang, Hae-Yun Jung, Kyung-Soon Park |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-07-01
|
Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/10/7/e004825.full |
Similar Items
-
ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancer
by: Hae-Yun Jung, et al.
Published: (2023-12-01) -
The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics
by: Joo Dong Park, et al.
Published: (2023-07-01) -
Chemical priming of natural killer cells with branched polyethylenimine for cancer immunotherapy
by: Jin-Ho Choi, et al.
Published: (2022-08-01) -
ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes
by: Minwook Lee, et al.
Published: (2022-03-01) -
Functional Link between miR-200a and ELK3 Regulates the Metastatic Nature of Breast Cancer
by: Hyung-Keun Kim, et al.
Published: (2020-05-01)