The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design
Abstract Balamuthia mandrillaris, a pathogenic free-living amoeba, causes cutaneous skin lesions as well as granulomatous amoebic encephalitis, a ‘brain-eating’ disease. As with the other known pathogenic free-living amoebas (Naegleria fowleri and Acanthamoeba species), drug discovery efforts to com...
Main Authors: | Isabelle Q. Phan, Christopher A. Rice, Justin Craig, Rooksana E. Noorai, Jacquelyn R. McDonald, Sandhya Subramanian, Logan Tillery, Lynn K. Barrett, Vijay Shankar, James C. Morris, Wesley C. Van Voorhis, Dennis E. Kyle, Peter J. Myler |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-99903-8 |
Similar Items
-
Balamuthia mandrillaris trophozoites ingest human neuronal cells via a trogocytosis-independent mechanism
by: Worakamol Pengsart, et al.
Published: (2022-06-01) -
Fatal Balamuthia mandrillaris Encephalitis
by: Binoy Yohannan, et al.
Published: (2019-01-01) -
Amoebic Encephalitis Caused by Balamuthia mandrillaris
by: Su Jung Kum, et al.
Published: (2019-09-01) -
A case report of Balamuthia mandrillaris encephalitis
by: Zhen Li, et al.
Published: (2024-03-01) -
Balamuthia mandrillaris encephalitis in an uncontrolled diabetic patient
by: Valli Mani, et al.
Published: (2021-01-01)