Effect of polycystic ovary syndrome on increased risk of cardiovascular disease

Introduction and purpose: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women. It is a very complex disease in which hormonal disorders result in a number of metabolic dysfunctions and malfunctioning of the ovaries. This can lead to infertility, miscarriage and a...

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Main Authors: Anna Maciak, Piotr Pawłucki, Paulina Cuper, Michał Sekuła, Błażej Dziurowicz, Michalina Cuper
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-08-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/45427
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author Anna Maciak
Piotr Pawłucki
Paulina Cuper
Michał Sekuła
Błażej Dziurowicz
Michalina Cuper
author_facet Anna Maciak
Piotr Pawłucki
Paulina Cuper
Michał Sekuła
Błażej Dziurowicz
Michalina Cuper
author_sort Anna Maciak
collection DOAJ
description Introduction and purpose: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women. It is a very complex disease in which hormonal disorders result in a number of metabolic dysfunctions and malfunctioning of the ovaries. This can lead to infertility, miscarriage and an increased risk of endometrial cancer. The aim of our work is to draw attention to the influence of PCOS on increased cardiovascular risk. Brief description of the state of knowledge: The occurrence of PCOS, especially uncontrolled pharmacologically and non-pharmacologically, may be associated with an increased cardiovascular risk. The literature describes a higher incidence of dyslipidemia, carbohydrate metabolism disorders, obesity, hypertension, chronic inflammation and oxidative stress. As a consequence, it can lead to the development of metabolic syndrome. All these factors negatively affect the risk of developing cardiovascular disease. To prevent this, it is necessary to use appropriate pharmacological and non-pharmacological methods in women diagnosed with PCOS. Conclusion: The mechanism of PCOS is complex and its development is influenced by genetic, endocrine, metabolic and environmental factors. The lack of proper diagnosis and the lack of treatment of PCOS is associated with numerous metabolic complications and an increased risk of cardiovascular diseases. Due to the poorly understood pathomechanism of this disease, further long-term studies are needed to help diagnose and treat PCOS.
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spelling doaj.art-2f65014bceb144ca9b1b6ea8b9bd5b452023-09-05T10:49:08ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0145110.12775/JEHS.2023.45.01.020Effect of polycystic ovary syndrome on increased risk of cardiovascular diseaseAnna Maciak0Piotr Pawłucki1Paulina Cuper2Michał Sekuła3Błażej Dziurowicz4Michalina Cuper55 The Military Clinical Hospital with Polyclinic in Krakow, Wrocławska 1/3 Street, 30-901 Department of Diagnostic Medicine, John Paul 2Nd Hospital, Prądnicka Str 80, 31-202, Kraków, PolandBrothers Hospitallers of Saint John of God Hospital in Cracow; Trynitarska 11 Street, 31-061 Kraków, PolandNeurology Department, Independent Public Clinical Hospital No.4 in Lublin, Jaczewskiego 8 Str, 20-954 Lublin, PolandLesser Poland Orthopedic and Rehabilitation Hospital, Modrzewiowa 22 Av., 30-224 Kraków, PolandMedical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland Introduction and purpose: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women. It is a very complex disease in which hormonal disorders result in a number of metabolic dysfunctions and malfunctioning of the ovaries. This can lead to infertility, miscarriage and an increased risk of endometrial cancer. The aim of our work is to draw attention to the influence of PCOS on increased cardiovascular risk. Brief description of the state of knowledge: The occurrence of PCOS, especially uncontrolled pharmacologically and non-pharmacologically, may be associated with an increased cardiovascular risk. The literature describes a higher incidence of dyslipidemia, carbohydrate metabolism disorders, obesity, hypertension, chronic inflammation and oxidative stress. As a consequence, it can lead to the development of metabolic syndrome. All these factors negatively affect the risk of developing cardiovascular disease. To prevent this, it is necessary to use appropriate pharmacological and non-pharmacological methods in women diagnosed with PCOS. Conclusion: The mechanism of PCOS is complex and its development is influenced by genetic, endocrine, metabolic and environmental factors. The lack of proper diagnosis and the lack of treatment of PCOS is associated with numerous metabolic complications and an increased risk of cardiovascular diseases. Due to the poorly understood pathomechanism of this disease, further long-term studies are needed to help diagnose and treat PCOS. https://apcz.umk.pl/JEHS/article/view/45427polycystic ovary syndromecardiovascular diseasesmetabolic disordershyperandrogenism
spellingShingle Anna Maciak
Piotr Pawłucki
Paulina Cuper
Michał Sekuła
Błażej Dziurowicz
Michalina Cuper
Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
Journal of Education, Health and Sport
polycystic ovary syndrome
cardiovascular diseases
metabolic disorders
hyperandrogenism
title Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
title_full Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
title_fullStr Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
title_full_unstemmed Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
title_short Effect of polycystic ovary syndrome on increased risk of cardiovascular disease
title_sort effect of polycystic ovary syndrome on increased risk of cardiovascular disease
topic polycystic ovary syndrome
cardiovascular diseases
metabolic disorders
hyperandrogenism
url https://apcz.umk.pl/JEHS/article/view/45427
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AT michałsekuła effectofpolycysticovarysyndromeonincreasedriskofcardiovasculardisease
AT błazejdziurowicz effectofpolycysticovarysyndromeonincreasedriskofcardiovasculardisease
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