Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder

Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder

Abstract The association between capsaicin, the major natural pungent compound of chili peppers, and gastric cancer progression has engendered conflicting findings. In this work, we sought to explore the character of a high capsaicin diet in gastric cancer metastasis and its possible mechanism. The...

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Bibliographic Details
Main Authors: Rui Deng, Suyun Yu, Xingqiu Ruan, Huan Liu, Gangfan Zong, Peng Cheng, Ruizhi Tao, Wenxing Chen, Aiyun Wang, Yang Zhao, Zhonghong Wei, Yin Lu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cell Communication and Signaling
Subjects:
High capsaicin diet
Gastric cancer
Gut microbiota
TRPV1 channel
5-HT
Online Access:https://doi.org/10.1186/s12964-023-01265-3

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