Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis
Background: Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State (CHR), and Psychotic-Like Experience (PLE). This study aimed to compare the cognitive function in early stages of psychosis using the...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Schizophrenia Research: Cognition |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001324000039 |
| _version_ | 1797256399517908992 |
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| author | Sebastian Corral Pablo A. Gaspar Rolando I. Castillo-Passi Rocío Mayol Troncoso Adrian P. Mundt Yuriy Ignatyev Rodrigo R. Nieto Alicia Figueroa-Muñoz |
| author_facet | Sebastian Corral Pablo A. Gaspar Rolando I. Castillo-Passi Rocío Mayol Troncoso Adrian P. Mundt Yuriy Ignatyev Rodrigo R. Nieto Alicia Figueroa-Muñoz |
| author_sort | Sebastian Corral |
| collection | DOAJ |
| description | Background: Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State (CHR), and Psychotic-Like Experience (PLE). This study aimed to compare the cognitive function in early stages of psychosis using the Montreal Cognitive Assessment (MoCA), a low-cost and brief assessment tool of cognitive functions. Methods: A total of 154 individuals, including 35 with FEP, 38 CHR, 44 PLE, and 37 healthy controls (HC), were evaluated with the MoCA in Santiago, Chile. We calculated the mean total score of the MoCA and the standard deviation of the mean. Groups were assessed for a trend to lower scores in a pre-determined sequence (HC > PLE > CHR > FEP) using the Jonckheere-Terpstra test (TJT). Results: The mean total MoCA scores were 24.8 ± 3.3 in FEP, 26.4 ± 2.4 in CHR, 26.4 ± 2.3 in PLE, and 27.2 ± 1.8 in HC. The analyses revealed a significant trend (p < 0.05) toward lower MoCA individual domain scores and MoCA total scores in the following order: HC > PLE > CHR > FEP. The mean total scores of all groups were above the cut-off for cognitive impairment (22 points). Conclusions: The MoCA describes lower scores in cognition across early stages of psychosis and may be a useful low-cost assessment instrument in early intervention centers of poorly resourced settings. |
| first_indexed | 2024-03-08T09:41:32Z |
| format | Article |
| id | doaj.art-2f67d94e355549fcb9c7f64e659ba117 |
| institution | Directory Open Access Journal |
| issn | 2215-0013 |
| language | English |
| last_indexed | 2024-04-24T22:21:08Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj.art-2f67d94e355549fcb9c7f64e659ba1172024-03-20T06:09:25ZengElsevierSchizophrenia Research: Cognition2215-00132024-06-0136100302Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosisSebastian Corral0Pablo A. Gaspar1Rolando I. Castillo-Passi2Rocío Mayol Troncoso3Adrian P. Mundt4Yuriy Ignatyev5Rodrigo R. Nieto6Alicia Figueroa-Muñoz7Clínica Psiquiátrica Universitaria, Hospital Clínico de la Universidad de Chile, Santiago, Chile; Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Departamento de Psicología, Universidad de La Serena, La Serena, ChileDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Departamento de Neurociencias, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Núcleo Milenio para Mejorar la Salud Mental de Adolescentes y Jóvenes, Imhay, Chile; Corresponding author at: University of Chile, Deparment of Psychiatry and Mental Health, Av. La Paz 1003, Recoleta, Santiago, Chile.Clínica Psiquiátrica Universitaria, Hospital Clínico de la Universidad de Chile, Santiago, Chile; Núcleo Milenio para Mejorar la Salud Mental de Adolescentes y Jóvenes, Imhay, Chile; Departamento de Neurología y Psiquiatría, Clínica Alemana, Universidad del Desarrollo, Santiago, RM, ChileClínica Psiquiátrica Universitaria, Hospital Clínico de la Universidad de Chile, Santiago, Chile; Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Núcleo Milenio para Mejorar la Salud Mental de Adolescentes y Jóvenes, Imhay, Chile; Facultad de Psicología, Universidad Alberto Hurtado, Santiago, ChileDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Facultad de Medicina, Universidad Diego Portales, Santiago, ChileDepartment of Psychiatry and Psychotherapy, Brandenburg Medical School Theodor Fontane, Immanuel Klinik Rüdersdorf, Rüdersdorf, Germany; Faculty for Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Neuruppin, GermanyClínica Psiquiátrica Universitaria, Hospital Clínico de la Universidad de Chile, Santiago, Chile; Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Departamento de Neurociencias, Facultad de Medicina, Universidad de Chile, Santiago, ChileClínica Psiquiátrica Universitaria, Hospital Clínico de la Universidad de Chile, Santiago, ChileBackground: Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State (CHR), and Psychotic-Like Experience (PLE). This study aimed to compare the cognitive function in early stages of psychosis using the Montreal Cognitive Assessment (MoCA), a low-cost and brief assessment tool of cognitive functions. Methods: A total of 154 individuals, including 35 with FEP, 38 CHR, 44 PLE, and 37 healthy controls (HC), were evaluated with the MoCA in Santiago, Chile. We calculated the mean total score of the MoCA and the standard deviation of the mean. Groups were assessed for a trend to lower scores in a pre-determined sequence (HC > PLE > CHR > FEP) using the Jonckheere-Terpstra test (TJT). Results: The mean total MoCA scores were 24.8 ± 3.3 in FEP, 26.4 ± 2.4 in CHR, 26.4 ± 2.3 in PLE, and 27.2 ± 1.8 in HC. The analyses revealed a significant trend (p < 0.05) toward lower MoCA individual domain scores and MoCA total scores in the following order: HC > PLE > CHR > FEP. The mean total scores of all groups were above the cut-off for cognitive impairment (22 points). Conclusions: The MoCA describes lower scores in cognition across early stages of psychosis and may be a useful low-cost assessment instrument in early intervention centers of poorly resourced settings.http://www.sciencedirect.com/science/article/pii/S2215001324000039SchizophreniaFirst episode psychosisPsychotic-like experiencesMoCANeurocognitive impairmentNeuropsychological assessment |
| spellingShingle | Sebastian Corral Pablo A. Gaspar Rolando I. Castillo-Passi Rocío Mayol Troncoso Adrian P. Mundt Yuriy Ignatyev Rodrigo R. Nieto Alicia Figueroa-Muñoz Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis Schizophrenia Research: Cognition Schizophrenia First episode psychosis Psychotic-like experiences MoCA Neurocognitive impairment Neuropsychological assessment |
| title | Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis |
| title_full | Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis |
| title_fullStr | Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis |
| title_full_unstemmed | Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis |
| title_short | Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis |
| title_sort | montreal cognitive assessment moca as a screening tool for cognitive impairment in early stages of psychosis |
| topic | Schizophrenia First episode psychosis Psychotic-like experiences MoCA Neurocognitive impairment Neuropsychological assessment |
| url | http://www.sciencedirect.com/science/article/pii/S2215001324000039 |
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