Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance
Background: Streptococcus pyogenes is a significant pathogen that causes various types of human diseases which range from mild to fatal illness. This work was designed to assess the value of symptoms in the prediction of disease and macrolides resistance. Methods: We conducted a cross-sectional hosp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Biomedical and Biotechnology Research Journal |
| Subjects: | |
| Online Access: | http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2022;volume=6;issue=4;spage=515;epage=519;aulast=Ahmed |
| _version_ | 1797955049025961984 |
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| author | Elnaim Bushra Ahmed Elsir Ali Abu Groun Babiker Saad Almugadam Nadir Abuzeid |
| author_facet | Elnaim Bushra Ahmed Elsir Ali Abu Groun Babiker Saad Almugadam Nadir Abuzeid |
| author_sort | Elnaim Bushra Ahmed |
| collection | DOAJ |
| description | Background: Streptococcus pyogenes is a significant pathogen that causes various types of human diseases which range from mild to fatal illness. This work was designed to assess the value of symptoms in the prediction of disease and macrolides resistance. Methods: We conducted a cross-sectional hospital-based study during 2020–2021 in Kosti Teaching Hospital (Kosti city, Sudan) to evaluate the link between symptoms with Group A Streptococcus (GAS) infection. Streptococcal tonsillitis was diagnosed by throat swabs culture, and macrolides resistance was detected by phenotypic and genotypic methods. Results: There was no significant variation in the mean of reported symptoms between gender and residence. Macrolides resistance and resistance genes had no significant effect on symptoms. On correlation analysis, age and education level were negatively correlated with symptoms score. Conclusions: The study highlights the link between symptoms with GAS tonsillitis and suggests the requirement for more care in children. |
| first_indexed | 2024-04-10T23:28:14Z |
| format | Article |
| id | doaj.art-2f6e645b68d1441d87cb401cb5c6a9a5 |
| institution | Directory Open Access Journal |
| issn | 2588-9834 2588-9842 |
| language | English |
| last_indexed | 2024-04-10T23:28:14Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Biomedical and Biotechnology Research Journal |
| spelling | doaj.art-2f6e645b68d1441d87cb401cb5c6a9a52023-01-12T11:21:07ZengWolters Kluwer Medknow PublicationsBiomedical and Biotechnology Research Journal2588-98342588-98422022-01-016451551910.4103/bbrj.bbrj_237_22Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistanceElnaim Bushra AhmedElsir Ali Abu GrounBabiker Saad AlmugadamNadir AbuzeidBackground: Streptococcus pyogenes is a significant pathogen that causes various types of human diseases which range from mild to fatal illness. This work was designed to assess the value of symptoms in the prediction of disease and macrolides resistance. Methods: We conducted a cross-sectional hospital-based study during 2020–2021 in Kosti Teaching Hospital (Kosti city, Sudan) to evaluate the link between symptoms with Group A Streptococcus (GAS) infection. Streptococcal tonsillitis was diagnosed by throat swabs culture, and macrolides resistance was detected by phenotypic and genotypic methods. Results: There was no significant variation in the mean of reported symptoms between gender and residence. Macrolides resistance and resistance genes had no significant effect on symptoms. On correlation analysis, age and education level were negatively correlated with symptoms score. Conclusions: The study highlights the link between symptoms with GAS tonsillitis and suggests the requirement for more care in children.http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2022;volume=6;issue=4;spage=515;epage=519;aulast=Ahmedclinical featuresmacrolides resistancestreptococcal tonsillitissudan |
| spellingShingle | Elnaim Bushra Ahmed Elsir Ali Abu Groun Babiker Saad Almugadam Nadir Abuzeid Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance Biomedical and Biotechnology Research Journal clinical features macrolides resistance streptococcal tonsillitis sudan |
| title | Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| title_full | Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| title_fullStr | Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| title_full_unstemmed | Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| title_short | Performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| title_sort | performance of clinical features as predictor of streptococcal tonsillitis and macrolides resistance |
| topic | clinical features macrolides resistance streptococcal tonsillitis sudan |
| url | http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2022;volume=6;issue=4;spage=515;epage=519;aulast=Ahmed |
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