High Glucose Induces Oxidative Stress That Alters Glycocalyx Proteoglycan Levels in Primary Rat Retinal Microvascular Endothelial Cells and in Isolated Ophthalmic Arteries

High Glucose Induces Oxidative Stress That Alters Glycocalyx Proteoglycan Levels in Primary Rat Retinal Microvascular Endothelial Cells and in Isolated Ophthalmic Arteries

Our purpose in this study was to identify the role played by oxidative stress in the changes to proteoglycans that occur under hyperglycemic conditions, using primary rat retinal microvascular endothelial cells (RRMEC) and cultured ophthalmic arteries. The cells and blood vessels obtained from rats...

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Bibliographic Details
Main Authors: Ivan A. Alvarez, Minsup Lee, Randa S. Eshaq, Wendy Leskova, Norman R. Harris
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pathophysiology
Subjects:
diabetic retinopathy
oxidative stress
glycocalyx
matrix metalloproteinase-9
Online Access:https://www.mdpi.com/1873-149X/31/1/7

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