Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates

Introduction: We aimed to evaluate the clinical characteristics of patients presenting with DKA and COVID-19 infection and describe the clinical outcomes compared to those without COVID-19. Methods: A retrospective study in a single tertiary care hospital in Dubai was conducted on patients admitted...

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Main Authors: Hana AL Sughaiyer, Abeer AL Haj, Samia Murad Ibrahim Abdulrahman
Format: Article
Language:English
Published: Karger Publishers 2023-08-01
Series:Dubai Diabetes and Endocrinology Journal
Subjects:
Online Access:https://beta.karger.com/Article/FullText/531683
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author Hana AL Sughaiyer
Abeer AL Haj
Samia Murad Ibrahim Abdulrahman
author_facet Hana AL Sughaiyer
Abeer AL Haj
Samia Murad Ibrahim Abdulrahman
author_sort Hana AL Sughaiyer
collection DOAJ
description Introduction: We aimed to evaluate the clinical characteristics of patients presenting with DKA and COVID-19 infection and describe the clinical outcomes compared to those without COVID-19. Methods: A retrospective study in a single tertiary care hospital in Dubai was conducted on patients admitted between 1st March 2020 and 30th July 2020 with a diagnosis of DKA with and without COVID-19 infection. Results: A total of 32 patients with DKA were identified. Eleven patients had a positive COVID-19 test and 21 patients were negative. The majority of DKA patients were males (84.4%). In the COVID-19 group, the mean age was 41.3 years old. Seven patients had preexisting diabetes (63.7%) and 4 patients (36.4%) had newly diagnosed diabetes. COVID-19 patients had a longer median length of hospital stay (7 days vs. 4 days; p = 0.278), shorter duration of DKA (16 h vs. 24 h; p = 0.043), and higher mortality (18.2% vs. 0%; p = 0.047). Conclusion: COVID-19 infection can precipitate DKA in patients with either newly diagnosed or preexisting diabetes. DKA patients with COVID-19 infection had higher mortality compared to those without COVID-19. This should urge physicians to be more vigilant in assessing the glycemic status of patients presenting with COVID-19 infection.
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spelling doaj.art-2f7381d540ef45c797d17b4a544d844b2023-09-07T07:56:39ZengKarger PublishersDubai Diabetes and Endocrinology Journal2673-17382023-08-011910.1159/000531683531683Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab EmiratesHana AL Sughaiyer0Abeer AL Haj1Samia Murad Ibrahim Abdulrahman2Department of Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab EmiratesDepartment of Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab EmiratesDepartment of Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab EmiratesIntroduction: We aimed to evaluate the clinical characteristics of patients presenting with DKA and COVID-19 infection and describe the clinical outcomes compared to those without COVID-19. Methods: A retrospective study in a single tertiary care hospital in Dubai was conducted on patients admitted between 1st March 2020 and 30th July 2020 with a diagnosis of DKA with and without COVID-19 infection. Results: A total of 32 patients with DKA were identified. Eleven patients had a positive COVID-19 test and 21 patients were negative. The majority of DKA patients were males (84.4%). In the COVID-19 group, the mean age was 41.3 years old. Seven patients had preexisting diabetes (63.7%) and 4 patients (36.4%) had newly diagnosed diabetes. COVID-19 patients had a longer median length of hospital stay (7 days vs. 4 days; p = 0.278), shorter duration of DKA (16 h vs. 24 h; p = 0.043), and higher mortality (18.2% vs. 0%; p = 0.047). Conclusion: COVID-19 infection can precipitate DKA in patients with either newly diagnosed or preexisting diabetes. DKA patients with COVID-19 infection had higher mortality compared to those without COVID-19. This should urge physicians to be more vigilant in assessing the glycemic status of patients presenting with COVID-19 infection.https://beta.karger.com/Article/FullText/531683diabetic ketoacidosiscovid-19characteristicsoutcomes
spellingShingle Hana AL Sughaiyer
Abeer AL Haj
Samia Murad Ibrahim Abdulrahman
Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
Dubai Diabetes and Endocrinology Journal
diabetic ketoacidosis
covid-19
characteristics
outcomes
title Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
title_full Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
title_fullStr Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
title_full_unstemmed Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
title_short Diabetic Ketoacidosis in COVID-19 Patients: Clinical Characteristics and Outcomes – A Retrospective Study in a Single Tertiary Care Hospital, Dubai, United Arab Emirates
title_sort diabetic ketoacidosis in covid 19 patients clinical characteristics and outcomes a retrospective study in a single tertiary care hospital dubai united arab emirates
topic diabetic ketoacidosis
covid-19
characteristics
outcomes
url https://beta.karger.com/Article/FullText/531683
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