Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature
<p>Abstract</p> <p/> <p>Hepatitis C virus (HCV) infection becomes chronic in about 85 % of individuals as demonstrated by the persistence of HCV. It is necesseray to treat acute hepatitis C infection. Interferon-α is generally used for the treatment of acute HCV infection.<...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2002-10-01
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| Series: | Annals of Clinical Microbiology and Antimicrobials |
| Online Access: | http://www.ann-clinmicrob.com/content/1/1/3 |
| _version_ | 1818919472151396352 |
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| author | Sunbul Mustafa Esen Saban Bayirli Derya Leblebicioglu Hakan Eroglu Cafer |
| author_facet | Sunbul Mustafa Esen Saban Bayirli Derya Leblebicioglu Hakan Eroglu Cafer |
| author_sort | Sunbul Mustafa |
| collection | DOAJ |
| description | <p>Abstract</p> <p/> <p>Hepatitis C virus (HCV) infection becomes chronic in about 85 % of individuals as demonstrated by the persistence of HCV. It is necesseray to treat acute hepatitis C infection. Interferon-α is generally used for the treatment of acute HCV infection.</p> <p>Case presentation</p> <p>A 55-year-old woman with a history of fatique and icter was diagnosed as acute hepatitis C virus infection. She was treated with interferon-α 2b 3 million unite sc three times in a week and ribavirin 1000 mg daily for 6 months. Within 2 weeks of therapy, the alanine aminotransferase (ALT) had became normal. At the end of the 3 months of therapy, HCV RNA was negative and remained negative 6 months after the end of interferon treatment (sustained response).</p> <p>Conclusion</p> <p>This report suggests that interferon-α 2b and ribavirin may have a role in treatment of acute hepatitis C virus infection.</p> |
| first_indexed | 2024-12-20T01:06:24Z |
| format | Article |
| id | doaj.art-2f738c81e1e24571a44bf7da5299af90 |
| institution | Directory Open Access Journal |
| issn | 1476-0711 |
| language | English |
| last_indexed | 2024-12-20T01:06:24Z |
| publishDate | 2002-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of Clinical Microbiology and Antimicrobials |
| spelling | doaj.art-2f738c81e1e24571a44bf7da5299af902022-12-21T19:58:50ZengBMCAnnals of Clinical Microbiology and Antimicrobials1476-07112002-10-0111310.1186/1476-0711-1-3Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literatureSunbul MustafaEsen SabanBayirli DeryaLeblebicioglu HakanEroglu Cafer<p>Abstract</p> <p/> <p>Hepatitis C virus (HCV) infection becomes chronic in about 85 % of individuals as demonstrated by the persistence of HCV. It is necesseray to treat acute hepatitis C infection. Interferon-α is generally used for the treatment of acute HCV infection.</p> <p>Case presentation</p> <p>A 55-year-old woman with a history of fatique and icter was diagnosed as acute hepatitis C virus infection. She was treated with interferon-α 2b 3 million unite sc three times in a week and ribavirin 1000 mg daily for 6 months. Within 2 weeks of therapy, the alanine aminotransferase (ALT) had became normal. At the end of the 3 months of therapy, HCV RNA was negative and remained negative 6 months after the end of interferon treatment (sustained response).</p> <p>Conclusion</p> <p>This report suggests that interferon-α 2b and ribavirin may have a role in treatment of acute hepatitis C virus infection.</p>http://www.ann-clinmicrob.com/content/1/1/3 |
| spellingShingle | Sunbul Mustafa Esen Saban Bayirli Derya Leblebicioglu Hakan Eroglu Cafer Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature Annals of Clinical Microbiology and Antimicrobials |
| title | Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature |
| title_full | Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature |
| title_fullStr | Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature |
| title_full_unstemmed | Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature |
| title_short | Treatment of acute hepatitis C virus infection with interferon-α 2b and ribavirin: Case report and review of the literature |
| title_sort | treatment of acute hepatitis c virus infection with interferon α 2b and ribavirin case report and review of the literature |
| url | http://www.ann-clinmicrob.com/content/1/1/3 |
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