Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease
Nowadays vaccination of the population living in the endemic regions and widespread implementation of the potent therapies for the emergency prophylaxis and treatment into the clinical practice are regarded as the basic efficient and cost-effective measures for Ebola epidemic spread control. Objecti...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2015-09-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/254 |
| _version_ | 1826922425387843584 |
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| author | A. A. Petrov V. N. Lebedev T. M. Plekhanova L. F. Stovba G. V. Borisevich O. N. Sidorova O. V. Chukhralya S. V. Borisevich |
| author_facet | A. A. Petrov V. N. Lebedev T. M. Plekhanova L. F. Stovba G. V. Borisevich O. N. Sidorova O. V. Chukhralya S. V. Borisevich |
| author_sort | A. A. Petrov |
| collection | DOAJ |
| description | Nowadays vaccination of the population living in the endemic regions and widespread implementation of the potent therapies for the emergency prophylaxis and treatment into the clinical practice are regarded as the basic efficient and cost-effective measures for Ebola epidemic spread control. Objective of the review is to analyze current state of the development of aids for the immediate prophylaxis and treatment of Ebola fever. Focus area of the activities is the construction of drugs on the basis of virus-specific anti-bodies (including monoclonal), small interfering RNA, and anti-sense phosphordiamidate morpholine oligomers and interferons. The paper discusses the most significant achievements in this sphere. |
| first_indexed | 2024-03-08T13:43:15Z |
| format | Article |
| id | doaj.art-2f7d6c63f16f49a6bb49b1eb6e25a00c |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2025-02-17T14:09:39Z |
| publishDate | 2015-09-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-2f7d6c63f16f49a6bb49b1eb6e25a00c2024-12-24T12:09:51ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2015-09-01039810310.21055/0370-1069-2015-3-98-103254Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus DiseaseA. A. Petrov0V. N. Lebedev1T. M. Plekhanova2L. F. Stovba3G. V. Borisevich4O. N. Sidorova5O. V. Chukhralya6S. V. Borisevich7The 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseThe 48th Central Research Institute of the RF Ministry of DefenseNowadays vaccination of the population living in the endemic regions and widespread implementation of the potent therapies for the emergency prophylaxis and treatment into the clinical practice are regarded as the basic efficient and cost-effective measures for Ebola epidemic spread control. Objective of the review is to analyze current state of the development of aids for the immediate prophylaxis and treatment of Ebola fever. Focus area of the activities is the construction of drugs on the basis of virus-specific anti-bodies (including monoclonal), small interfering RNA, and anti-sense phosphordiamidate morpholine oligomers and interferons. The paper discusses the most significant achievements in this sphere.https://journal.microbe.ru/jour/article/view/254вирус эболалекарственные средстваэкстренная профилактика и лечениевирусспецифические антителамоноклональные антителамалые интерферирующие рнкантисмысловые фосфордиамидатные морфолиновые олигомерыebola virushemorrhagic fevermedical productsemergency prophylaxis and treatmentvirus-specific antibodiesmonoclonal antibodiessmall interfering rnaanti-sense phosphordiamidate morpholine oligomers |
| spellingShingle | A. A. Petrov V. N. Lebedev T. M. Plekhanova L. F. Stovba G. V. Borisevich O. N. Sidorova O. V. Chukhralya S. V. Borisevich Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease Проблемы особо опасных инфекций вирус эбола лекарственные средства экстренная профилактика и лечение вирусспецифические антитела моноклональные антитела малые интерферирующие рнк антисмысловые фосфордиамидатные морфолиновые олигомеры ebola virus hemorrhagic fever medical products emergency prophylaxis and treatment virus-specific antibodies monoclonal antibodies small interfering rna anti-sense phosphordiamidate morpholine oligomers |
| title | Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease |
| title_full | Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease |
| title_fullStr | Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease |
| title_full_unstemmed | Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease |
| title_short | Current State of the Development of Therapies for Emergency Prophylaxis and Treatment of Ebola Virus Disease |
| title_sort | current state of the development of therapies for emergency prophylaxis and treatment of ebola virus disease |
| topic | вирус эбола лекарственные средства экстренная профилактика и лечение вирусспецифические антитела моноклональные антитела малые интерферирующие рнк антисмысловые фосфордиамидатные морфолиновые олигомеры ebola virus hemorrhagic fever medical products emergency prophylaxis and treatment virus-specific antibodies monoclonal antibodies small interfering rna anti-sense phosphordiamidate morpholine oligomers |
| url | https://journal.microbe.ru/jour/article/view/254 |
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