Histone Methyltransferase DOT1L Is Involved in Larval Molting and Second Stage Nymphal Feeding in <i>Ornithodoros moubata</i>

Histone Methyltransferase DOT1L Is Involved in Larval Molting and Second Stage Nymphal Feeding in <i>Ornithodoros moubata</i>

Epigenetic mechanisms have not been characterized in ticks despite their importance as vectors of human and animal diseases worldwide. Our investigation identifies and functionally characterizes the orthologue of S-adenosylmethionine (SAM) binding methyltransferase enzyme, disruptor of telomeric sil...

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Bibliographic Details
Main Authors: Julia Gobl, Deepak Kumar Sinha, Radek Sima, Jan Perner, Petr Kopáček, James J Valdés, Ryan O. M. Rego, Alejandro Cabezas-Cruz
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Vaccines
Subjects:
<i>Ornithodoros moubata</i>
histone methyltransferase
DOT1L
Online Access:https://www.mdpi.com/2076-393X/8/2/157

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