High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature
Background: Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report: We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined...
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| Format: | Article |
| Language: | English |
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Palacký University Olomouc, Faculty of Medicine and Dentistry
2016-12-01
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| Series: | Biomedical Papers |
| Subjects: | |
| Online Access: | https://biomed.papers.upol.cz/artkey/bio-201604-0020_High-grade_urothelial_bladder_cancer_in_children_A_case_report_and_critical_analysis_of_the_literature.php |
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| author | Milan Kral Jaroslav Michalek Jozef Skarda Tomas Tichy Oldrich Smakal Roman Kodet Vladimir Student |
| author_facet | Milan Kral Jaroslav Michalek Jozef Skarda Tomas Tichy Oldrich Smakal Roman Kodet Vladimir Student |
| author_sort | Milan Kral |
| collection | DOAJ |
| description | Background: Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report: We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined for painless hematuria. Transurethral resection of the tumor was performed and T1 high grade urothelial cancer with osseous metaplasia was found in definitive specimens. During the 2-year follow-up, there has been no recurrence. Typical characteristics of the most prevalent bladder tumors are presented. Conclusion: Despite its low incidence and low prevalence bladder cancer in children is a very serious condition which must not be missed in the differential diagnosis of hematuria or urinary tract infection. It is vital to differentiate urothelial cancer from hamartoma and nephrogenic adenoma and, particularly in osseous metaplasia, from sarcomatoid carcinoma. Especially in high-grade cancers, precise TUR of the tumor with a careful follow-up is essential to detect cancer recurrence and reduce progression. |
| first_indexed | 2024-12-13T00:59:05Z |
| format | Article |
| id | doaj.art-2f870a3e196c48cc84ed82e2d2f9ed13 |
| institution | Directory Open Access Journal |
| issn | 1213-8118 1804-7521 |
| language | English |
| last_indexed | 2024-12-13T00:59:05Z |
| publishDate | 2016-12-01 |
| publisher | Palacký University Olomouc, Faculty of Medicine and Dentistry |
| record_format | Article |
| series | Biomedical Papers |
| spelling | doaj.art-2f870a3e196c48cc84ed82e2d2f9ed132022-12-22T00:04:43ZengPalacký University Olomouc, Faculty of Medicine and DentistryBiomedical Papers1213-81181804-75212016-12-01160457858210.5507/bp.2016.045bio-201604-0020High-grade urothelial bladder cancer in children: A case report and critical analysis of the literatureMilan Kral0Jaroslav Michalek1Jozef Skarda2Tomas Tichy3Oldrich Smakal4Roman Kodet5Vladimir Student6Department of Urology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicDepartment of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicDepartment of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicDepartment of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicDepartment of Urology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicDepartment of Pathology and Molecular Medicine, Faculty Hospital Motol and 2nd Faculty of Medicine, Charles University in Prague, Czech RepublicDepartment of Urology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech RepublicBackground: Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report: We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined for painless hematuria. Transurethral resection of the tumor was performed and T1 high grade urothelial cancer with osseous metaplasia was found in definitive specimens. During the 2-year follow-up, there has been no recurrence. Typical characteristics of the most prevalent bladder tumors are presented. Conclusion: Despite its low incidence and low prevalence bladder cancer in children is a very serious condition which must not be missed in the differential diagnosis of hematuria or urinary tract infection. It is vital to differentiate urothelial cancer from hamartoma and nephrogenic adenoma and, particularly in osseous metaplasia, from sarcomatoid carcinoma. Especially in high-grade cancers, precise TUR of the tumor with a careful follow-up is essential to detect cancer recurrence and reduce progression.https://biomed.papers.upol.cz/artkey/bio-201604-0020_High-grade_urothelial_bladder_cancer_in_children_A_case_report_and_critical_analysis_of_the_literature.phpbladder cancertreatmentchildrenpathology |
| spellingShingle | Milan Kral Jaroslav Michalek Jozef Skarda Tomas Tichy Oldrich Smakal Roman Kodet Vladimir Student High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature Biomedical Papers bladder cancer treatment children pathology |
| title | High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature |
| title_full | High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature |
| title_fullStr | High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature |
| title_full_unstemmed | High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature |
| title_short | High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature |
| title_sort | high grade urothelial bladder cancer in children a case report and critical analysis of the literature |
| topic | bladder cancer treatment children pathology |
| url | https://biomed.papers.upol.cz/artkey/bio-201604-0020_High-grade_urothelial_bladder_cancer_in_children_A_case_report_and_critical_analysis_of_the_literature.php |
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