Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

Annexin 1 (ANXA1) is an endogenous anti-inflammatory protein implicated in cancer. ANXA1 was previously shown to be regulated by hsa-miR-196a. However, whether ANXA1 itself regulates microRNA (miR) expression is unknown. Therefore, we investigated the regulation of miR by ANXA1 in MCF7 breast cancer...

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Bibliographic Details
Main Authors: Durkeshwari Anbalagan, Gracemary Yap, Yi Yuan, Vijay K Pandey, Wai Hoe Lau, Suruchi Arora, Pradeep Bist, Justin S B Wong, Gautam Sethi, Peter M Nissom, Peter E Lobie, Lina H K Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275173?pdf=render

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