Recommendations for using standardised phenotypes in genetic association studies

Recommendations for using standardised phenotypes in genetic association studies

<p>Abstract</p> <p>Genetic association studies of complex traits often rely on standardised quantitative phenotypes, such as percentage of predicted forced expiratory volume and body mass index to measure an underlying trait of interest (eg lung function, obesity). These phenotypes...

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Bibliographic Details
Main Authors: Naylor Melissa G, Weiss Scott T, Lange Christoph
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Human Genomics
Subjects:
body mass index
confounding factors
covariate adjustment
forced expiratory volume
heritable quantitative traits
Online Access:http://www.humgenomics.com/content/3/4/308

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