Left Bundle Branch Ablation Guided by a Three-Dimensional Mapping System: A Novel Method for Establishing a Heart Failure Animal Model
Objective: Few studies have been conducted to establish animal models of left bundle branch block by using three-dimensional mapping systems. This research was aimed at creating a canine left bundle branch block model by using a three-dimensional mapping system. Materials and Methods: We used a th...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2023-10-01
|
| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0066 |
| Summary: | Objective: Few studies have been conducted to establish animal models of left bundle branch block by using three-dimensional mapping systems. This research was aimed at creating a canine left bundle branch block model by using a three-dimensional mapping system. Materials and Methods: We used a three-dimensional mapping system to map and ablate the left bundle branch in beagles. Results: Ten canines underwent radiofrequency ablation, among which left bundle branch block was successfully established in eight, one experienced ventricular fibrillation, and one developed third-degree atrioventricular block. The maximum HV interval measured within the left ventricle was 29.00 ± 2.93 ms, and the LBP-V interval at the ablation site was 20.63 ± 2.77 ms. The LBP-V interval at the ablation target was 71.08% of the maximum HV interval. Conclusion: This three-dimensional mapping system is a reliable and effective guide for ablation of the left bundle branch in dogs. |
|---|---|
| ISSN: | 2009-8618 2009-8782 |