Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report
Abstract Background Hepatocellular carcinoma (HCC) patients with metastases to the cervical lymph nodes are extremely rare, and its clinical course is characterized by rapidly progressive disease. Hence, there have been no reports of metastatic cervical lymph node recurrence indicated after a long p...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2021-12-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-021-01352-y |
| _version_ | 1819177193258876928 |
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| author | Kiyonori Tanoue Yota Kawasaki Yoichi Yamasaki Satoshi Iino Masahiko Sakoda Yuko Mataki Tetsuya Idichi Yoshiaki Kita Yuto Hozaka Akihiro Nakajo Takaaki Arigami Hiroshi Kurahara Takao Ohtsuka |
| author_facet | Kiyonori Tanoue Yota Kawasaki Yoichi Yamasaki Satoshi Iino Masahiko Sakoda Yuko Mataki Tetsuya Idichi Yoshiaki Kita Yuto Hozaka Akihiro Nakajo Takaaki Arigami Hiroshi Kurahara Takao Ohtsuka |
| author_sort | Kiyonori Tanoue |
| collection | DOAJ |
| description | Abstract Background Hepatocellular carcinoma (HCC) patients with metastases to the cervical lymph nodes are extremely rare, and its clinical course is characterized by rapidly progressive disease. Hence, there have been no reports of metastatic cervical lymph node recurrence indicated after a long postoperative surveillance period. Case presentation The patient was a 63-year-old male who underwent right hepatectomy for HCC of the right upper lobe. Three years after resection, metastatic lymph node recurrence was detected in the subdiaphragm, superior mediastinum, and right cervical lymph nodes. The patient underwent excisional biopsy of the cervical lymph node, followed by molecular-targeted therapy and radiation therapy. Lenvatinib reduced the size of all metastatic lymph nodes and the patient survived for a relatively long period of 43 months after the recurrence was detected. Conclusions After resection of HCC in the right upper lobe, there is the possibility of metastatic lymph node recurrence in unusual sites, including the cervical region, and lenvatinib may be effective in those recurrences. |
| first_indexed | 2024-12-22T21:22:46Z |
| format | Article |
| id | doaj.art-2f8d4f52773840789a51082d575823ee |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-22T21:22:46Z |
| publishDate | 2021-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-2f8d4f52773840789a51082d575823ee2022-12-21T18:12:08ZengSpringerOpenSurgical Case Reports2198-77932021-12-01711510.1186/s40792-021-01352-yPostoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case reportKiyonori Tanoue0Yota Kawasaki1Yoichi Yamasaki2Satoshi Iino3Masahiko Sakoda4Yuko Mataki5Tetsuya Idichi6Yoshiaki Kita7Yuto Hozaka8Akihiro Nakajo9Takaaki Arigami10Hiroshi Kurahara11Takao Ohtsuka12Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Kagoshima City HospitalDepartment of Digestive Surgery, Kagoshima Kouseiren HospitalDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Onco-biological Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Graduate School of Medical and Dental SciencesAbstract Background Hepatocellular carcinoma (HCC) patients with metastases to the cervical lymph nodes are extremely rare, and its clinical course is characterized by rapidly progressive disease. Hence, there have been no reports of metastatic cervical lymph node recurrence indicated after a long postoperative surveillance period. Case presentation The patient was a 63-year-old male who underwent right hepatectomy for HCC of the right upper lobe. Three years after resection, metastatic lymph node recurrence was detected in the subdiaphragm, superior mediastinum, and right cervical lymph nodes. The patient underwent excisional biopsy of the cervical lymph node, followed by molecular-targeted therapy and radiation therapy. Lenvatinib reduced the size of all metastatic lymph nodes and the patient survived for a relatively long period of 43 months after the recurrence was detected. Conclusions After resection of HCC in the right upper lobe, there is the possibility of metastatic lymph node recurrence in unusual sites, including the cervical region, and lenvatinib may be effective in those recurrences.https://doi.org/10.1186/s40792-021-01352-yHepatocellular carcinomaRecurrenceExtrahepatic metastasisCervical lymph node metastasis |
| spellingShingle | Kiyonori Tanoue Yota Kawasaki Yoichi Yamasaki Satoshi Iino Masahiko Sakoda Yuko Mataki Tetsuya Idichi Yoshiaki Kita Yuto Hozaka Akihiro Nakajo Takaaki Arigami Hiroshi Kurahara Takao Ohtsuka Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report Surgical Case Reports Hepatocellular carcinoma Recurrence Extrahepatic metastasis Cervical lymph node metastasis |
| title | Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report |
| title_full | Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report |
| title_fullStr | Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report |
| title_full_unstemmed | Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report |
| title_short | Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report |
| title_sort | postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma a case report |
| topic | Hepatocellular carcinoma Recurrence Extrahepatic metastasis Cervical lymph node metastasis |
| url | https://doi.org/10.1186/s40792-021-01352-y |
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