Thermotolerance improvement of engineered Saccharomyces cerevisiae ERG5 Delta ERG4 Delta ERG3 Delta, molecular mechanism, and its application in corn ethanol production

Thermotolerance improvement of engineered Saccharomyces cerevisiae ERG5 Delta ERG4 Delta ERG3 Delta, molecular mechanism, and its application in corn ethanol production

Abstract Background The thermotolerant yeast is beneficial in terms of efficiency improvement of processes and reduction of costs, while Saccharomyces cerevisiae does not efficiently grow and ferment at high-temperature conditions. The sterol composition alteration from ergosterol to fecosterol in t...

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Bibliographic Details
Main Authors: Peizhou Yang, Wenjing Wu, Jianchao Chen, Suwei Jiang, Zhi Zheng, Yanhong Deng, Jiuling Lu, Hu Wang, Yong Zhou, Yuyou Geng, Kanglin Wang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Thermotolerant improvement
Saccharomyces cerevisiae
CRISPR–Cas9 approach
Transcriptomics
Ethanol production
Ergosterol
Online Access:https://doi.org/10.1186/s13068-023-02312-4

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