Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review
Abstract Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive secondary metabolites. It contributed to many biotechnological applications and its metabolites are used in the synthesis of certain pharmaceuticals...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | Fungal Biology and Biotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40694-023-00153-2 |
| _version_ | 1797860006917308416 |
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| author | Khadiga Amr Nehal Ibrahim Ahmed M. Elissawy Abdel Nasser B. Singab |
| author_facet | Khadiga Amr Nehal Ibrahim Ahmed M. Elissawy Abdel Nasser B. Singab |
| author_sort | Khadiga Amr |
| collection | DOAJ |
| description | Abstract Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive secondary metabolites. It contributed to many biotechnological applications and its metabolites are used in the synthesis of certain pharmaceuticals and food products, in addition to its useful uses in fermentation processes. There are about 346 compounds identified from marine and terrestrial-derived A. terreus from 1987 until 2022, 172 compounds of them proved a vast array of bioactivity. This review aimed to create an up-to-date comprehensive literature data of A. terreus’s secondary metabolites classes supported by its different bioactivity data to be a scientific record for the next work in drug discovery. |
| first_indexed | 2024-04-09T21:38:46Z |
| format | Article |
| id | doaj.art-2f952a96c32f41f2ac9e112908697bc2 |
| institution | Directory Open Access Journal |
| issn | 2054-3085 |
| language | English |
| last_indexed | 2024-04-09T21:38:46Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Fungal Biology and Biotechnology |
| spelling | doaj.art-2f952a96c32f41f2ac9e112908697bc22023-03-26T11:05:47ZengBMCFungal Biology and Biotechnology2054-30852023-03-0110113310.1186/s40694-023-00153-2Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive reviewKhadiga Amr0Nehal Ibrahim1Ahmed M. Elissawy2Abdel Nasser B. Singab3Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams UniversityAbstract Aspergillus terreus microorganism represents a promising prospective source for drug discovery since it is rich in diverse kinds of bioactive secondary metabolites. It contributed to many biotechnological applications and its metabolites are used in the synthesis of certain pharmaceuticals and food products, in addition to its useful uses in fermentation processes. There are about 346 compounds identified from marine and terrestrial-derived A. terreus from 1987 until 2022, 172 compounds of them proved a vast array of bioactivity. This review aimed to create an up-to-date comprehensive literature data of A. terreus’s secondary metabolites classes supported by its different bioactivity data to be a scientific record for the next work in drug discovery.https://doi.org/10.1186/s40694-023-00153-2A. terreusFungal endophytesBiological activityNatural productsDrug discovery |
| spellingShingle | Khadiga Amr Nehal Ibrahim Ahmed M. Elissawy Abdel Nasser B. Singab Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review Fungal Biology and Biotechnology A. terreus Fungal endophytes Biological activity Natural products Drug discovery |
| title | Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review |
| title_full | Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review |
| title_fullStr | Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review |
| title_full_unstemmed | Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review |
| title_short | Unearthing the fungal endophyte Aspergillus terreus for chemodiversity and medicinal prospects: a comprehensive review |
| title_sort | unearthing the fungal endophyte aspergillus terreus for chemodiversity and medicinal prospects a comprehensive review |
| topic | A. terreus Fungal endophytes Biological activity Natural products Drug discovery |
| url | https://doi.org/10.1186/s40694-023-00153-2 |
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