Multifunctional Freestanding Microprobes for Potential Biological Applications
Deep-level sensors for detecting the local temperatures of inner organs and tissues of an animal are rarely reported. In this paper, we present a method to fabricate multifunctional micro-probes with standard cleanroom procedures, using a piece of stainless-steel foil as the substrate. On each of th...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/19/10/2328 |
| _version_ | 1811306179983310848 |
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| author | Nana Yang Zhenhai Wang Jingjing Xu Lijiang Gui Zhiqiang Tang Yuqi Zhang Ming Yi Shuanglin Yue Shengyong Xu |
| author_facet | Nana Yang Zhenhai Wang Jingjing Xu Lijiang Gui Zhiqiang Tang Yuqi Zhang Ming Yi Shuanglin Yue Shengyong Xu |
| author_sort | Nana Yang |
| collection | DOAJ |
| description | Deep-level sensors for detecting the local temperatures of inner organs and tissues of an animal are rarely reported. In this paper, we present a method to fabricate multifunctional micro-probes with standard cleanroom procedures, using a piece of stainless-steel foil as the substrate. On each of the as-fabricated micro-probes, arrays of thermocouples made of Pd–Cr thin-film stripes with reliable thermal sensing functions were built, together with Pd electrode openings for detecting electrical signals. The as-fabricated sword-shaped freestanding microprobes with length up to 30 mm showed excellent mechanical strength and elastic properties when they were inserted into the brain and muscle tissues of live rats, as well as suitable electrochemical properties and, therefore, are promising for potential biological applications. |
| first_indexed | 2024-04-13T08:39:43Z |
| format | Article |
| id | doaj.art-2f96547c43484184bda7af8a5c043f72 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-13T08:39:43Z |
| publishDate | 2019-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-2f96547c43484184bda7af8a5c043f722022-12-22T02:53:55ZengMDPI AGSensors1424-82202019-05-011910232810.3390/s19102328s19102328Multifunctional Freestanding Microprobes for Potential Biological ApplicationsNana Yang0Zhenhai Wang1Jingjing Xu2Lijiang Gui3Zhiqiang Tang4Yuqi Zhang5Ming Yi6Shuanglin Yue7Shengyong Xu8Key Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaKey Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaKey Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaDepartment of Micro-Nano Fabrication Technology, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, ChinaKey Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaNeuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing 100083, ChinaNeuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing 100083, ChinaKey Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaKey Laboratory for the Physics & Chemistry of Nanodevices and Department of Electronics, Peking University, Beijing 100871, ChinaDeep-level sensors for detecting the local temperatures of inner organs and tissues of an animal are rarely reported. In this paper, we present a method to fabricate multifunctional micro-probes with standard cleanroom procedures, using a piece of stainless-steel foil as the substrate. On each of the as-fabricated micro-probes, arrays of thermocouples made of Pd–Cr thin-film stripes with reliable thermal sensing functions were built, together with Pd electrode openings for detecting electrical signals. The as-fabricated sword-shaped freestanding microprobes with length up to 30 mm showed excellent mechanical strength and elastic properties when they were inserted into the brain and muscle tissues of live rats, as well as suitable electrochemical properties and, therefore, are promising for potential biological applications.https://www.mdpi.com/1424-8220/19/10/2328freestanding micro-probestainless steelthermocoupleelectrodebiological application |
| spellingShingle | Nana Yang Zhenhai Wang Jingjing Xu Lijiang Gui Zhiqiang Tang Yuqi Zhang Ming Yi Shuanglin Yue Shengyong Xu Multifunctional Freestanding Microprobes for Potential Biological Applications Sensors freestanding micro-probe stainless steel thermocouple electrode biological application |
| title | Multifunctional Freestanding Microprobes for Potential Biological Applications |
| title_full | Multifunctional Freestanding Microprobes for Potential Biological Applications |
| title_fullStr | Multifunctional Freestanding Microprobes for Potential Biological Applications |
| title_full_unstemmed | Multifunctional Freestanding Microprobes for Potential Biological Applications |
| title_short | Multifunctional Freestanding Microprobes for Potential Biological Applications |
| title_sort | multifunctional freestanding microprobes for potential biological applications |
| topic | freestanding micro-probe stainless steel thermocouple electrode biological application |
| url | https://www.mdpi.com/1424-8220/19/10/2328 |
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