Immunogenicity of a Dendrimer B2T Peptide Harboring a T-Cell Epitope From FMDV Non-structural Protein 3D

Immunogenicity of a Dendrimer B2T Peptide Harboring a T-Cell Epitope From FMDV Non-structural Protein 3D

Synthetic dendrimer peptides are a promising strategy to develop new FMD vaccines. A dendrimer peptide, termed B2T-3A, which harbors two copies of the major FMDV antigenic B-cell site [VP1 (140–158)], covalently linked to a heterotypic T-cell from the non-structural protein 3A [3A (21–35)], has been...

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Bibliographic Details
Main Authors: Rodrigo Cañas-Arranz, Patricia de León, Mar Forner, Sira Defaus, María J. Bustos, Elisa Torres, David Andreu, Esther Blanco, Francisco Sobrino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Veterinary Science
Subjects:
FMDV
vaccines
dendrimer peptides
T-cell epitopes
swine
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2020.00498/full

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