Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.

Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.

BACKGROUND:Cluster of differentiation 36 (CD36) is a transmembrane glycoprotein involved in many biological processes, such as platelet biology, angiogenesis and in the aetiopathology of atherosclerosis and cardiovascular diseases. Toll-like receptors (TLRs) are one of the most important receptors o...

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Main Authors: Maximiliano J Jimenez-Dalmaroni, Nengming Xiao, Adam L Corper, Petra Verdino, Gary D Ainge, Dave S Larsen, Gavin F Painter, Pauline M Rudd, Raymond A Dwek, Kasper Hoebe, Bruce Beutler, Ian A Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2760212?pdf=render

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