The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism

The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism

Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs). However, it is still challenging to maintain high productivity...

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Bibliographic Details
Main Authors:	Hui-Ning Liu, Wei-Hua Dong, Yan Lin, Zhao-Hui Zhang, Tian-Yun Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-03-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	CHO cells miRNA recombinant protein cell engineering protein quality
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.832065/full

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