CircSCAPER knockdown attenuates IL-1β-induced chondrocyte injury by miR-127-5p/TLR4 axis in osteoarthritis

CircSCAPER knockdown attenuates IL-1β-induced chondrocyte injury by miR-127-5p/TLR4 axis in osteoarthritis

Purpose Osteoarthritis (OA) is a chronic inflammatory degenerative disease characterized by articular cartilage degradation. Circular RNAs have been shown to play significant roles in OA process. Herein, this work aimed to investigate the potential role and mechanism of circSCAPER in OA progression....

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Bibliographic Details
Main Authors: Yuchang Zhang, Ping Zhao, Sen Li, Xiangqian Mu, Huaqi Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Autoimmunity
Subjects:
circscaper
mir-127-5p
tlr4
chondrocyte
osteoarthritis
extracellular matrix
Online Access:http://dx.doi.org/10.1080/08916934.2022.2103798

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