The protective effects of silymarin nanoemulsion on 5-fluorouracil-induced gastrointestinal toxicity in rats

The protective effects of silymarin nanoemulsion on 5-fluorouracil-induced gastrointestinal toxicity in rats

5-Fluorouracil (5FUra) is the third most popular chemotherapeutic component employed to treat solid tumors. In the present study, we aimed to appraise the silymarin (SM) and silymarin nanoemulsion (SMN) effect on 5FUra-induced gastrointestinal toxicity in adult male rats. A total of 30 male Wistar r...

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Bibliographic Details
Main Authors: Soheila Safarpour, Samaneh Safarpour, Ali Akbar Moghadamnia, Sohrab Kazemi, Anahita Ebrahimpour, Fatemeh Shirafkan
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Saudi Pharmaceutical Journal
Subjects:
Silymarin
Gastrointestinal toxicity
Oxidative stress
IL-2
TNF-α
5-Fluorouracil
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423001573

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http://www.sciencedirect.com/science/article/pii/S1319016423001573

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