Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration

Preclinical Evaluation of UDCA-Containing Oral Formulation in Mice for the Treatment of Wet Age-Related Macular Degeneration

As a posterior ocular disease, wet age-related macular degeneration (WAMD) has been known to be related to vision loss, accompanying ocular complications. The intravitreous injection of VEGF antibodies has been reported to be an effective treatment to relieve symptoms of WAMD. However, the limitatio...

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Bibliographic Details
Main Authors: Pooja Maharjan, Daseul Kim, Minki Jin, Hwi Jin Ko, Yeong Ho Song, Yoonjin Lee, Byul-Nim Ahn, Si-Kyung Kim, Yujin Lee, Meong Cheol Shin, Kyoung Ah Min, JaeWook Yang
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceutics
Subjects:
ocular treatment
ursodeoxycholic acid
tauroursodeoxycholic acid
bile acid
age-related macular degeneration
choroidal neovascularization
Online Access:https://www.mdpi.com/1999-4923/11/11/561

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