Influence of chemical structure and mechanism of hydrolysis on pharmacological activity and toxicological profile of approved platinum drugs

The problems with platinum complexes are resistance and toxicity of anticancer therapy. The aim of current study is the comparison of the influence of chemical structure and mechanism of hydrolysis on pharmacological activity and toxicological profile of approved in platinum drugs: Cisplatin, Carbop...

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Bibliographic Details
Main Authors: Danka Obreshkova, Stefka Ivanova, Pavlina Yordanova-Laleva
Format: Article
Language:English
Published: Pensoft Publishers 2022-07-01
Series:Pharmacia
Subjects:
Online Access:https://pharmacia.pensoft.net/article/87494/download/pdf/