(2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide
The asymmetric unit of the title compound, C21H20N4O3S, contains two independent molecules. The dihedral angles between the two benzene rings are 47.6 (1) and 30.2 (1)°, the corresponding values between the p-methoxybenzene and thiadiazol rings are 12.3 (1) and...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2008-10-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536808027803 |
| _version_ | 1819291409538088960 |
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| author | Cheng-Mei Liu Guo-Gang Tu Hui-Ming Huang Gang Li Shao-Hua Li |
| author_facet | Cheng-Mei Liu Guo-Gang Tu Hui-Ming Huang Gang Li Shao-Hua Li |
| author_sort | Cheng-Mei Liu |
| collection | DOAJ |
| description | The asymmetric unit of the title compound, C21H20N4O3S, contains two independent molecules. The dihedral angles between the two benzene rings are 47.6 (1) and 30.2 (1)°, the corresponding values between the p-methoxybenzene and thiadiazol rings are 12.3 (1) and 24.7 (1)°, respectively, for the two molecules. The conformations of the N—H and C=O bonds are anti with respect to each other. The enone groups show a trans configuration. The crystal structure is stabilized by N—H...O and N—H...N interactions. The absolute structure could not be determined from the X-ray data but the absolute configuration has been assigned by reference to an unchanging chiral centre in the synthetic procedure. |
| first_indexed | 2024-12-24T03:38:11Z |
| format | Article |
| id | doaj.art-2fadb2b4fbb249989552dd2c4470e1cc |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-24T03:38:11Z |
| publishDate | 2008-10-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-2fadb2b4fbb249989552dd2c4470e1cc2022-12-21T17:17:00ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682008-10-016410o1887o188710.1107/S1600536808027803(2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamideCheng-Mei LiuGuo-Gang TuHui-Ming HuangGang LiShao-Hua LiThe asymmetric unit of the title compound, C21H20N4O3S, contains two independent molecules. The dihedral angles between the two benzene rings are 47.6 (1) and 30.2 (1)°, the corresponding values between the p-methoxybenzene and thiadiazol rings are 12.3 (1) and 24.7 (1)°, respectively, for the two molecules. The conformations of the N—H and C=O bonds are anti with respect to each other. The enone groups show a trans configuration. The crystal structure is stabilized by N—H...O and N—H...N interactions. The absolute structure could not be determined from the X-ray data but the absolute configuration has been assigned by reference to an unchanging chiral centre in the synthetic procedure.http://scripts.iucr.org/cgi-bin/paper?S1600536808027803 |
| spellingShingle | Cheng-Mei Liu Guo-Gang Tu Hui-Ming Huang Gang Li Shao-Hua Li (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide Acta Crystallographica Section E |
| title | (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide |
| title_full | (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide |
| title_fullStr | (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide |
| title_full_unstemmed | (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide |
| title_short | (2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide |
| title_sort | 2r 2 cinnamoylamino n 5 4 methoxyphenyl 1 3 4 thiadiazol 2 yl propanamide |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536808027803 |
| work_keys_str_mv | AT chengmeiliu 2r2cinnamoylaminon54methoxyphenyl134thiadiazol2ylpropanamide AT guogangtu 2r2cinnamoylaminon54methoxyphenyl134thiadiazol2ylpropanamide AT huiminghuang 2r2cinnamoylaminon54methoxyphenyl134thiadiazol2ylpropanamide AT gangli 2r2cinnamoylaminon54methoxyphenyl134thiadiazol2ylpropanamide AT shaohuali 2r2cinnamoylaminon54methoxyphenyl134thiadiazol2ylpropanamide |