Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis.

Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed to demonstrate changes in NEP and associated neur...

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Detaylı Bibliyografya
Asıl Yazarlar: Zeynep Gök Sargın, Nuray Erin, Gokhan Tazegul, Gülsüm Özlem Elpek, Bülent Yıldırım
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2017-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC5726735?pdf=render