Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis.

Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed to demonstrate changes in NEP and associated neur...

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Príomhchruthaitheoirí: Zeynep Gök Sargın, Nuray Erin, Gokhan Tazegul, Gülsüm Özlem Elpek, Bülent Yıldırım
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2017-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC5726735?pdf=render