CD4+CCR8+ Tregs in ovarian cancer: a potential effector Tregs for immune regulation

CD4+CCR8+ Tregs in ovarian cancer: a potential effector Tregs for immune regulation

Abstract Background Tregs are key drivers of immunosuppression in solid tumors. As an important chemokine receptor on Tregs, the regulatory effect of CCR8 on tumor immunity has received more and more attention. However, the current research on CCR8 in the immune microenvironment of ovarian cancer ha...

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Bibliographic Details
Main Authors: Shuna Liu, Ziqi Tao, Jianfang Lou, Rong Li, Xin Fu, Juan Xu, Ting Wang, Lei Zhang, Wenwen Shang, Yepeng Mao, Fang Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Ovarian cancer
Regulatory T cells
CCR8
Gene expression profile
Chemokine
Online Access:https://doi.org/10.1186/s12967-023-04686-3

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