BCG revaccination of health workers in Brazil to improve innate immune responses against COVID-19: A structured summary of a study protocol for a randomised controlled trial

BCG revaccination of health workers in Brazil to improve innate immune responses against COVID-19: A structured summary of a study protocol for a randomised controlled trial

Abstract Objectives The BCG vaccine, widely used in Brazil in new-borns, induces adjuvant protection for several diseases, including childhood virus infections. BCG activates monocytes and innate memory NK cells which are crucial for the antiviral immune response. Therefore, strategies to prevent CO...

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Bibliographic Details
Main Authors: Ana Paula Junqueira-Kipnis, Laura Raniere Borges dos Anjos, Lília Cristina de Souza Barbosa, Adeliane Castro da Costa, Kellen Christina Malheiros Borges, Amanda da Rocha Oliveira Cardoso, Kaio Mota Ribeiro, Sarah Brena Aparecida Rosa, Carine de Castro Souza, Rogério Coutinho das Neves, Guylherme Saraiva, Sueli Meira da Silva, Erika Aparecida da Silveira, Marcelo Fouad Rabahi, Marcus Barreto Conte, André Kipnis
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Trials
Subjects:
COVID-19
Randomised controlled trial
protocol
BCG revaccination
health workers
innate immune response
Online Access:http://link.springer.com/article/10.1186/s13063-020-04822-0

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