A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA.

A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNA.

<h4>Background</h4>Vascular endothelial growth factor-A (VEGF) is one of the key regulators of tumor development, hence it is considered to be an important therapeutic target for cancer treatment. However, clinical trials have suggested that anti-VEGF monotherapy was less effective than...

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Bibliographic Details
Main Authors: Kiyoshi Masuda, Shigetada Teshima-Kondo, Mina Mukaijo, Naoko Yamagishi, Yoshiko Nishikawa, Kensei Nishida, Tomoko Kawai, Kazuhito Rokutan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18494554/?tool=EBI

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