Assessment of night vision problems in patients with congenital stationary night blindness.
Congenital Stationary Night Blindness (CSNB) is a retinal disorder caused by a signal transmission defect between photoreceptors and bipolar cells. CSNB can be subdivided in CSNB2 (rod signal transmission reduced) and CSNB1 (rod signal transmission absent). The present study is the first in which ni...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3643903?pdf=render |
| _version_ | 1818846917753307136 |
|---|---|
| author | Mieke M C Bijveld Maria M van Genderen Frank P Hoeben Amir A Katzin Ruth M A van Nispen Frans C C Riemslag Astrid M L Kappers |
| author_facet | Mieke M C Bijveld Maria M van Genderen Frank P Hoeben Amir A Katzin Ruth M A van Nispen Frans C C Riemslag Astrid M L Kappers |
| author_sort | Mieke M C Bijveld |
| collection | DOAJ |
| description | Congenital Stationary Night Blindness (CSNB) is a retinal disorder caused by a signal transmission defect between photoreceptors and bipolar cells. CSNB can be subdivided in CSNB2 (rod signal transmission reduced) and CSNB1 (rod signal transmission absent). The present study is the first in which night vision problems are assessed in CSNB patients in a systematic way, with the purpose of improving rehabilitation for these patients. We assessed the night vision problems of 13 CSNB2 patients and 9 CSNB1 patients by means of a questionnaire on low luminance situations. We furthermore investigated their dark adapted visual functions by the Goldmann Weekers dark adaptation curve, a dark adapted static visual field, and a two-dimensional version of the "Light Lab". In the latter test, a digital image of a living room with objects was projected on a screen. While increasing the luminance of the image, we asked the patients to report on detection and recognition of objects. The questionnaire showed that the CSNB2 patients hardly experienced any night vision problems, while all CSNB1 patients experienced some problems although they generally did not describe them as severe. The three scotopic tests showed minimally to moderately decreased dark adapted visual functions in the CSNB2 patients, with differences between patients. In contrast, the dark adapted visual functions of the CSNB1 patients were more severely affected, but showed almost no differences between patients. The results from the "2D Light Lab" showed that all CSNB1 patients were blind at low intensities (equal to starlight), but quickly regained vision at higher intensities (full moonlight). Just above their dark adapted thresholds both CSNB1 and CSNB2 patients had normal visual fields. From the results we conclude that night vision problems in CSNB, in contrast to what the name suggests, are not conspicuous and generally not disabling. |
| first_indexed | 2024-12-19T05:53:10Z |
| format | Article |
| id | doaj.art-2fbacc0c497a4118bdcbb3bb5e6b7c8a |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-19T05:53:10Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-2fbacc0c497a4118bdcbb3bb5e6b7c8a2022-12-21T20:33:32ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0185e6292710.1371/journal.pone.0062927Assessment of night vision problems in patients with congenital stationary night blindness.Mieke M C BijveldMaria M van GenderenFrank P HoebenAmir A KatzinRuth M A van NispenFrans C C RiemslagAstrid M L KappersCongenital Stationary Night Blindness (CSNB) is a retinal disorder caused by a signal transmission defect between photoreceptors and bipolar cells. CSNB can be subdivided in CSNB2 (rod signal transmission reduced) and CSNB1 (rod signal transmission absent). The present study is the first in which night vision problems are assessed in CSNB patients in a systematic way, with the purpose of improving rehabilitation for these patients. We assessed the night vision problems of 13 CSNB2 patients and 9 CSNB1 patients by means of a questionnaire on low luminance situations. We furthermore investigated their dark adapted visual functions by the Goldmann Weekers dark adaptation curve, a dark adapted static visual field, and a two-dimensional version of the "Light Lab". In the latter test, a digital image of a living room with objects was projected on a screen. While increasing the luminance of the image, we asked the patients to report on detection and recognition of objects. The questionnaire showed that the CSNB2 patients hardly experienced any night vision problems, while all CSNB1 patients experienced some problems although they generally did not describe them as severe. The three scotopic tests showed minimally to moderately decreased dark adapted visual functions in the CSNB2 patients, with differences between patients. In contrast, the dark adapted visual functions of the CSNB1 patients were more severely affected, but showed almost no differences between patients. The results from the "2D Light Lab" showed that all CSNB1 patients were blind at low intensities (equal to starlight), but quickly regained vision at higher intensities (full moonlight). Just above their dark adapted thresholds both CSNB1 and CSNB2 patients had normal visual fields. From the results we conclude that night vision problems in CSNB, in contrast to what the name suggests, are not conspicuous and generally not disabling.http://europepmc.org/articles/PMC3643903?pdf=render |
| spellingShingle | Mieke M C Bijveld Maria M van Genderen Frank P Hoeben Amir A Katzin Ruth M A van Nispen Frans C C Riemslag Astrid M L Kappers Assessment of night vision problems in patients with congenital stationary night blindness. PLoS ONE |
| title | Assessment of night vision problems in patients with congenital stationary night blindness. |
| title_full | Assessment of night vision problems in patients with congenital stationary night blindness. |
| title_fullStr | Assessment of night vision problems in patients with congenital stationary night blindness. |
| title_full_unstemmed | Assessment of night vision problems in patients with congenital stationary night blindness. |
| title_short | Assessment of night vision problems in patients with congenital stationary night blindness. |
| title_sort | assessment of night vision problems in patients with congenital stationary night blindness |
| url | http://europepmc.org/articles/PMC3643903?pdf=render |
| work_keys_str_mv | AT miekemcbijveld assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT mariamvangenderen assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT frankphoeben assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT amirakatzin assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT ruthmavannispen assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT fransccriemslag assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness AT astridmlkappers assessmentofnightvisionproblemsinpatientswithcongenitalstationarynightblindness |