Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications
Enzyme-assisted extraction (EAE) involves the use of hydrolytic enzymes for the degradation of the cell wall or other cell components. This supports the diffusion of the solvent into the plant or fungal material, leading to easier elution of its metabolites. This technique has been gaining increasin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/7/3232 |
| _version_ | 1797440524221677568 |
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| author | Agnieszka Łubek-Nguyen Wojciech Ziemichód Marta Olech |
| author_facet | Agnieszka Łubek-Nguyen Wojciech Ziemichód Marta Olech |
| author_sort | Agnieszka Łubek-Nguyen |
| collection | DOAJ |
| description | Enzyme-assisted extraction (EAE) involves the use of hydrolytic enzymes for the degradation of the cell wall or other cell components. This supports the diffusion of the solvent into the plant or fungal material, leading to easier elution of its metabolites. This technique has been gaining increasing attention, as it is considered an eco-friendly and cost-effective improvement on classical or modern extraction methods. Its promising application in improving the recovery of different classes of bioactive metabolites (e.g., polyphenols, carotenoids, polysaccharides, proteins, components of essential oil, and terpenes) has been reported by many scientific papers. This review summarises information on the theoretical aspects of EAE (e.g., the components of the cell walls and the types of enzymes used) and the most recent discoveries in the effective involvement of enzyme-assisted extraction of natural products (plants, mushrooms, and animals) for nutraceutical and pharmaceutical applications. |
| first_indexed | 2024-03-09T12:10:25Z |
| format | Article |
| id | doaj.art-2fbb09d38100400394a61cedf06f3b01 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T12:10:25Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-2fbb09d38100400394a61cedf06f3b012023-11-30T22:52:51ZengMDPI AGApplied Sciences2076-34172022-03-01127323210.3390/app12073232Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical ApplicationsAgnieszka Łubek-Nguyen0Wojciech Ziemichód1Marta Olech2Department of Pharmaceutical Botany, Medical University of Lublin, 1 Chodźki Street, 20-093 Lublin, PolandDepartment of Pharmaceutical Botany, Medical University of Lublin, 1 Chodźki Street, 20-093 Lublin, PolandDepartment of Pharmaceutical Botany, Medical University of Lublin, 1 Chodźki Street, 20-093 Lublin, PolandEnzyme-assisted extraction (EAE) involves the use of hydrolytic enzymes for the degradation of the cell wall or other cell components. This supports the diffusion of the solvent into the plant or fungal material, leading to easier elution of its metabolites. This technique has been gaining increasing attention, as it is considered an eco-friendly and cost-effective improvement on classical or modern extraction methods. Its promising application in improving the recovery of different classes of bioactive metabolites (e.g., polyphenols, carotenoids, polysaccharides, proteins, components of essential oil, and terpenes) has been reported by many scientific papers. This review summarises information on the theoretical aspects of EAE (e.g., the components of the cell walls and the types of enzymes used) and the most recent discoveries in the effective involvement of enzyme-assisted extraction of natural products (plants, mushrooms, and animals) for nutraceutical and pharmaceutical applications.https://www.mdpi.com/2076-3417/12/7/3232extraction improvementenzymolysispectinolytic enzymesproteolytic enzymesgreen chemistry |
| spellingShingle | Agnieszka Łubek-Nguyen Wojciech Ziemichód Marta Olech Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications Applied Sciences extraction improvement enzymolysis pectinolytic enzymes proteolytic enzymes green chemistry |
| title | Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications |
| title_full | Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications |
| title_fullStr | Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications |
| title_full_unstemmed | Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications |
| title_short | Application of Enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compounds for Nutraceutical and Pharmaceutical Applications |
| title_sort | application of enzyme assisted extraction for the recovery of natural bioactive compounds for nutraceutical and pharmaceutical applications |
| topic | extraction improvement enzymolysis pectinolytic enzymes proteolytic enzymes green chemistry |
| url | https://www.mdpi.com/2076-3417/12/7/3232 |
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