Recruitment, Infiltration, and Cytotoxicity of HLA-Independent Killer Lymphocytes in Three-Dimensional Melanoma Models

Recruitment, Infiltration, and Cytotoxicity of HLA-Independent Killer Lymphocytes in Three-Dimensional Melanoma Models

Cancer adoptive cell therapy (ACT) with HLA-independent tumor killer lymphocytes is a promising approach, with intrinsic features potentially addressing crucial tumor-escape mechanisms of checkpoint inhibitors. Cytokine-induced Killer (CIK) and Natural Killer (NK) lymphocytes share similar tumor-kil...

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Bibliographic Details
Main Authors: Ilenia Iaia, Loretta Gammaitoni, Giulia Cattaneo, Lidia Giraudo, Chiara Donini, Erika Fiorino, Luca Primo, Fabrizio Carnevale-Schianca, Massimo Aglietta, Alberto Puliafito, Dario Sangiolo
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
3D models
melanoma
cell therapy
imaging
Online Access:https://www.mdpi.com/2072-6694/13/10/2302

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