Danon Disease Presenting as Eosinophilic Myocarditis

Danon Disease Presenting as Eosinophilic Myocarditis

A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardio...

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Bibliographic Details
Main Authors: Basilio Angulo-Lara, MD, Ramón Garrido-González, MD, Clara Salas Antón, MD, PhD, Juan Francisco Oteo-Domínguez, MD, Javier Segovia-Cubero, MD, PhD, Fernando Domínguez, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:JACC: Case Reports
Subjects:
Danon disease
endomyocardial biopsy (EMB)
eosinophilic myocarditis
genetic testing
inherited cardiomyopathies
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084923000402
Description
Summary:A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardiomyopathy and presented with worsening of her functional class. Finally, genetic testing unveiled an additional diagnosis: Danon disease. (Level of Difficulty: Advanced.)
ISSN:2666-0849

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