Danon Disease Presenting as Eosinophilic Myocarditis
A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | JACC: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666084923000402 |
| _version_ | 1797897211879620608 |
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| author | Basilio Angulo-Lara, MD Ramón Garrido-González, MD Clara Salas Antón, MD, PhD Juan Francisco Oteo-Domínguez, MD Javier Segovia-Cubero, MD, PhD Fernando Domínguez, MD, PhD |
| author_facet | Basilio Angulo-Lara, MD Ramón Garrido-González, MD Clara Salas Antón, MD, PhD Juan Francisco Oteo-Domínguez, MD Javier Segovia-Cubero, MD, PhD Fernando Domínguez, MD, PhD |
| author_sort | Basilio Angulo-Lara, MD |
| collection | DOAJ |
| description | A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardiomyopathy and presented with worsening of her functional class. Finally, genetic testing unveiled an additional diagnosis: Danon disease. (Level of Difficulty: Advanced.) |
| first_indexed | 2024-04-10T07:55:02Z |
| format | Article |
| id | doaj.art-2fbe851fcc1349b9a5032df8fe98b688 |
| institution | Directory Open Access Journal |
| issn | 2666-0849 |
| language | English |
| last_indexed | 2024-04-10T07:55:02Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Case Reports |
| spelling | doaj.art-2fbe851fcc1349b9a5032df8fe98b6882023-02-23T04:32:05ZengElsevierJACC: Case Reports2666-08492023-04-0111101765Danon Disease Presenting as Eosinophilic MyocarditisBasilio Angulo-Lara, MD0Ramón Garrido-González, MD1Clara Salas Antón, MD, PhD2Juan Francisco Oteo-Domínguez, MD3Javier Segovia-Cubero, MD, PhD4Fernando Domínguez, MD, PhD5Cardiology Department, Hospital Universitario Puerta de Hierro, Madrid, SpainCardiology Department, Hospital Universitario Puerta de Hierro, Madrid, SpainPathology Department, Hospital Universitario Puerta de Hierro, Madrid, SpainCardiology Department, Hospital Universitario Puerta de Hierro, Madrid, SpainCardiology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, SpainCardiology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain; Address for correspondence: Dr Fernando Dominguez, Department of Cardiology, Hospital Universitario Puerta de Hierro, Manuel de Falla, 2, Majadahonda, Madrid 28222, Spain.A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardiomyopathy and presented with worsening of her functional class. Finally, genetic testing unveiled an additional diagnosis: Danon disease. (Level of Difficulty: Advanced.)http://www.sciencedirect.com/science/article/pii/S2666084923000402Danon diseaseendomyocardial biopsy (EMB)eosinophilic myocarditisgenetic testinginherited cardiomyopathies |
| spellingShingle | Basilio Angulo-Lara, MD Ramón Garrido-González, MD Clara Salas Antón, MD, PhD Juan Francisco Oteo-Domínguez, MD Javier Segovia-Cubero, MD, PhD Fernando Domínguez, MD, PhD Danon Disease Presenting as Eosinophilic Myocarditis JACC: Case Reports Danon disease endomyocardial biopsy (EMB) eosinophilic myocarditis genetic testing inherited cardiomyopathies |
| title | Danon Disease Presenting as Eosinophilic Myocarditis |
| title_full | Danon Disease Presenting as Eosinophilic Myocarditis |
| title_fullStr | Danon Disease Presenting as Eosinophilic Myocarditis |
| title_full_unstemmed | Danon Disease Presenting as Eosinophilic Myocarditis |
| title_short | Danon Disease Presenting as Eosinophilic Myocarditis |
| title_sort | danon disease presenting as eosinophilic myocarditis |
| topic | Danon disease endomyocardial biopsy (EMB) eosinophilic myocarditis genetic testing inherited cardiomyopathies |
| url | http://www.sciencedirect.com/science/article/pii/S2666084923000402 |
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