Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases
Antivascular endothelial growth factor (VEGF) treatment is still used intravitreally worldwide for various neovascular diseases, despite other available, approved treatments. We performed a systematic search of the literature focused on visual physiology studies. We used the online biomedical search...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=7;spage=559;epage=568;aulast=Hong |
| _version_ | 1818928586277519360 |
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| author | In Hwan Hong Sung Pyo Park |
| author_facet | In Hwan Hong Sung Pyo Park |
| author_sort | In Hwan Hong |
| collection | DOAJ |
| description | Antivascular endothelial growth factor (VEGF) treatment is still used intravitreally worldwide for various neovascular diseases, despite other available, approved treatments. We performed a systematic search of the literature focused on visual physiology studies. We used the online biomedical search engine PubMed and searched key words including “M-chart,” “Preferential Hyperacuity Perimetry,” “microperimetry,” (MP) “electroretinography,” and “contrast sensitivity” to estimate treatment efficacy of anti-VEGF treatments in a quantitative manner. Many studies were identified which used a variety of methodologies, disease entities, injected agents, and patient populations, making it difficult to obtain a direct comparison of their results. However, favorable functional outcomes achieved using current quantitative methods would lend further confidence to the effectiveness of a treat-and-extend protocol using intravitreal anti-VEGF for the management of patients with neovascular diseases. Despite anti-VEGF's wide use, a well-designed longitudinal multicenter study to systematically evaluate and compare different physiological methods or parameters in patients with neovascular diseases is still lacking, though it would benefit therapeutic decisions. |
| first_indexed | 2024-12-20T03:31:16Z |
| format | Article |
| id | doaj.art-2fbf5009a83a42c89e068056099303db |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-20T03:31:16Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-2fbf5009a83a42c89e068056099303db2022-12-21T19:54:58ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892017-01-0165755956810.4103/ijo.IJO_278_17Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseasesIn Hwan HongSung Pyo ParkAntivascular endothelial growth factor (VEGF) treatment is still used intravitreally worldwide for various neovascular diseases, despite other available, approved treatments. We performed a systematic search of the literature focused on visual physiology studies. We used the online biomedical search engine PubMed and searched key words including “M-chart,” “Preferential Hyperacuity Perimetry,” “microperimetry,” (MP) “electroretinography,” and “contrast sensitivity” to estimate treatment efficacy of anti-VEGF treatments in a quantitative manner. Many studies were identified which used a variety of methodologies, disease entities, injected agents, and patient populations, making it difficult to obtain a direct comparison of their results. However, favorable functional outcomes achieved using current quantitative methods would lend further confidence to the effectiveness of a treat-and-extend protocol using intravitreal anti-VEGF for the management of patients with neovascular diseases. Despite anti-VEGF's wide use, a well-designed longitudinal multicenter study to systematically evaluate and compare different physiological methods or parameters in patients with neovascular diseases is still lacking, though it would benefit therapeutic decisions.http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=7;spage=559;epage=568;aulast=HongAntivascular endothelial growth factor treatmentmicroperimetry and contrast sensitivityquantitative analysis and electroretinography |
| spellingShingle | In Hwan Hong Sung Pyo Park Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases Indian Journal of Ophthalmology Antivascular endothelial growth factor treatment microperimetry and contrast sensitivity quantitative analysis and electroretinography |
| title | Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| title_full | Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| title_fullStr | Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| title_full_unstemmed | Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| title_short | Quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| title_sort | quantitative physiological measurements to evaluate the response of antivascular endothelial growth factor treatment in patients with neovascular diseases |
| topic | Antivascular endothelial growth factor treatment microperimetry and contrast sensitivity quantitative analysis and electroretinography |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=7;spage=559;epage=568;aulast=Hong |
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