HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM

Leptin is the satiety hormone, synthesized in the adipose tissue that reduces food intake, being involved in glucose and lipid metabolism. Hyperleptinemia correlates with obesity and represents a risk factor in the pathology of the cardiovascular system. Increased concentrations of leptin have bee...

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Main Authors: Daniela Miricescu, Alexandra Totan, Constantin Ștefani, Ana Maria Alexandra Stănescu, Maria Greabu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2019-12-01
Series:Romanian Medical Journal
Subjects:
Online Access:https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.4/RMJ_2019_4_Art-04.pdf
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author Daniela Miricescu
Alexandra Totan
Constantin Ștefani
Ana Maria Alexandra Stănescu
Maria Greabu
author_facet Daniela Miricescu
Alexandra Totan
Constantin Ștefani
Ana Maria Alexandra Stănescu
Maria Greabu
author_sort Daniela Miricescu
collection DOAJ
description Leptin is the satiety hormone, synthesized in the adipose tissue that reduces food intake, being involved in glucose and lipid metabolism. Hyperleptinemia correlates with obesity and represents a risk factor in the pathology of the cardiovascular system. Increased concentrations of leptin have been observed in patients with hypertension or atherosclerosis. In vitro studies suggest the angiogenic role of leptin. The purpose of this review is to present the metabolic effects of hyperleptinemia in the cardiovascular system.
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spelling doaj.art-2fc3a34d3eac43878f1e0b236f1f3fc42024-02-03T03:32:39ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2019-12-0166431832210.37897/RMJ.2019.4.4HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEMDaniela Miricescu0Alexandra Totan1Constantin Ștefani2Ana Maria Alexandra Stănescu3Maria Greabu4Disciplina Biochimie, Facultatea de Medicină Dentară, Universitatea de Medicină și Farmacie „Carol Davila“, București, RomâniaDisciplina Biochimie, Facultatea de Medicină Dentară, Universitatea de Medicină și Farmacie „Carol Davila“, București, RomâniaDepartamentul Medicină de Familie, Facultatea de Medicină Generală, Universitatea de Medicină și Farmacie „Carol Davila“, București, România; Spitalul Universitar de Urgență Militar Central „Dr. Carol Davila“, București, RomâniaDepartamentul Medicină de Familie, Facultatea de Medicină Generală, Universitatea de Medicină și Farmacie „Carol Davila“, București, RomâniaDisciplina Biochimie, Facultatea de Medicină Dentară, Universitatea de Medicină și Farmacie „Carol Davila“, București, RomâniaLeptin is the satiety hormone, synthesized in the adipose tissue that reduces food intake, being involved in glucose and lipid metabolism. Hyperleptinemia correlates with obesity and represents a risk factor in the pathology of the cardiovascular system. Increased concentrations of leptin have been observed in patients with hypertension or atherosclerosis. In vitro studies suggest the angiogenic role of leptin. The purpose of this review is to present the metabolic effects of hyperleptinemia in the cardiovascular system.https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.4/RMJ_2019_4_Art-04.pdfadipose tissuehyperleptinemiacardiovascular diseases
spellingShingle Daniela Miricescu
Alexandra Totan
Constantin Ștefani
Ana Maria Alexandra Stănescu
Maria Greabu
HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
Romanian Medical Journal
adipose tissue
hyperleptinemia
cardiovascular diseases
title HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
title_full HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
title_fullStr HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
title_full_unstemmed HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
title_short HYPERLEPTINEMIA AND CARDIOVASCULAR SYSTEM
title_sort hyperleptinemia and cardiovascular system
topic adipose tissue
hyperleptinemia
cardiovascular diseases
url https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.4/RMJ_2019_4_Art-04.pdf
work_keys_str_mv AT danielamiricescu hyperleptinemiaandcardiovascularsystem
AT alexandratotan hyperleptinemiaandcardiovascularsystem
AT constantinstefani hyperleptinemiaandcardiovascularsystem
AT anamariaalexandrastanescu hyperleptinemiaandcardiovascularsystem
AT mariagreabu hyperleptinemiaandcardiovascularsystem