Cancer and nutrition among children and adolescents in low- and middle-income countries
Objective : The primary purpose of this review is to investigate the relationships between cancer and nutrition in children and adolescents living in resource-poor, low- and middle-income countries (LMICs) in order to explore potential opportunities for interventions which could improve clinical out...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Hematology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/16078454.2022.2115437 |
| _version_ | 1811209828797775872 |
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| author | Ronald D. Barr Federico Antillon-Klussmann |
| author_facet | Ronald D. Barr Federico Antillon-Klussmann |
| author_sort | Ronald D. Barr |
| collection | DOAJ |
| description | Objective : The primary purpose of this review is to investigate the relationships between cancer and nutrition in children and adolescents living in resource-poor, low- and middle-income countries (LMICs) in order to explore potential opportunities for interventions which could improve clinical outcomes in this population.Method : The implications of overlapping age groups of children and adolescents with cancer are examined, as are the adverse influences of under-nutrition and socio-economic deprivation on the efficacy of treatment and cancer survival. Evidence suggestive of novel avenues to enhance prospects for cure, based on increased understanding of the dynamic of nutrition and cancer, is evaluated.Result : Cancer adds to the burden of under-nutrition in disadvantaged populations which is reflective, in large measure, on inadequate governmental expenditure on health which demands public-private partnerships and the use of hospital-based foundations. Structured approaches to the measurement of nutritional status and the design of effective programmes of nutritional supplementation are of proven benefit. Initial results from studies of the perturbed gut microbiome hold considerable promise for further gains.Conclusion A large minority of children with cancer in LMICs are never diagnosed and the same may be true of adolescents. Investing in the training of nutritionists will have substantial returns as will increasing access to essential medicines. Recognition of these challenges has stimulated WHO and other entities to devise major strategies for comprehensive changes in the care of children and adolescents with cancer in LMICs, offering realistic prospects for improved clinical outcomes. |
| first_indexed | 2024-04-12T04:45:34Z |
| format | Article |
| id | doaj.art-2fc9eb17a327490782973477aa12e0b0 |
| institution | Directory Open Access Journal |
| issn | 1607-8454 |
| language | English |
| last_indexed | 2024-04-12T04:45:34Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hematology |
| spelling | doaj.art-2fc9eb17a327490782973477aa12e0b02022-12-22T03:47:30ZengTaylor & Francis GroupHematology1607-84542022-12-0127198799310.1080/16078454.2022.2115437Cancer and nutrition among children and adolescents in low- and middle-income countriesRonald D. Barr0Federico Antillon-Klussmann1Departments of Pediatrics and Medicine, McMaster University, Hamilton, CanadaUnidad Nacional de Oncología Pediátrica, and School of Medicine, Francisco Marroquín University, Guatemala, GuatemalaObjective : The primary purpose of this review is to investigate the relationships between cancer and nutrition in children and adolescents living in resource-poor, low- and middle-income countries (LMICs) in order to explore potential opportunities for interventions which could improve clinical outcomes in this population.Method : The implications of overlapping age groups of children and adolescents with cancer are examined, as are the adverse influences of under-nutrition and socio-economic deprivation on the efficacy of treatment and cancer survival. Evidence suggestive of novel avenues to enhance prospects for cure, based on increased understanding of the dynamic of nutrition and cancer, is evaluated.Result : Cancer adds to the burden of under-nutrition in disadvantaged populations which is reflective, in large measure, on inadequate governmental expenditure on health which demands public-private partnerships and the use of hospital-based foundations. Structured approaches to the measurement of nutritional status and the design of effective programmes of nutritional supplementation are of proven benefit. Initial results from studies of the perturbed gut microbiome hold considerable promise for further gains.Conclusion A large minority of children with cancer in LMICs are never diagnosed and the same may be true of adolescents. Investing in the training of nutritionists will have substantial returns as will increasing access to essential medicines. Recognition of these challenges has stimulated WHO and other entities to devise major strategies for comprehensive changes in the care of children and adolescents with cancer in LMICs, offering realistic prospects for improved clinical outcomes.https://www.tandfonline.com/doi/10.1080/16078454.2022.2115437CancernutritionchildrenadolescentsLMICs |
| spellingShingle | Ronald D. Barr Federico Antillon-Klussmann Cancer and nutrition among children and adolescents in low- and middle-income countries Hematology Cancer nutrition children adolescents LMICs |
| title | Cancer and nutrition among children and adolescents in low- and middle-income countries |
| title_full | Cancer and nutrition among children and adolescents in low- and middle-income countries |
| title_fullStr | Cancer and nutrition among children and adolescents in low- and middle-income countries |
| title_full_unstemmed | Cancer and nutrition among children and adolescents in low- and middle-income countries |
| title_short | Cancer and nutrition among children and adolescents in low- and middle-income countries |
| title_sort | cancer and nutrition among children and adolescents in low and middle income countries |
| topic | Cancer nutrition children adolescents LMICs |
| url | https://www.tandfonline.com/doi/10.1080/16078454.2022.2115437 |
| work_keys_str_mv | AT ronalddbarr cancerandnutritionamongchildrenandadolescentsinlowandmiddleincomecountries AT federicoantillonklussmann cancerandnutritionamongchildrenandadolescentsinlowandmiddleincomecountries |