Study of acute toxicity and investigation of the presence of β-N-methylamino-L-alanine in the Gunnera manicata L. a species native to Southern Brazil

Study of acute toxicity and investigation of the presence of β-N-methylamino-L-alanine in the Gunnera manicata L. a species native to Southern Brazil

Gunnera (Gunneraceae) forms a complex association with the cyanobacterium Nostoc puctiforme L. Gunnera-Nostoc symbiosis is the only one reported involving a flowering plant, and results in the formation of the neurotoxic amino acid β-N-methylamino-L-alanine (BMAA). The species Gunnera manicata L., f...

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Bibliographic Details
Main Authors: Kristiane de Cássia Mariotti, Fabiano Barreto, Gabriela Cristina Schmitt, Ivomar Zancanaro, Eliane Dallegrave, Rodrigo Bustos Singer, Mirna Bainy Leal, Renata Pereira Limberger
Format: Article
Language:English
Published: Universidade de São Paulo 2011-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Gunnera manicata L
/toxicity
β-N-methylamino-L-alanine
Neurotoxins
Acute toxicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300021&tlng=en

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