Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging
QuanJiang Li,1,* Juan Song,2,* XinYou Li,1 TianYou Luo,1 Juan Peng,1 FaJin Lv,1 YongMei Li,1 ZhongXin Huang,1 AnRan Wang1 1Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China; 2Department of Gastroenterology &...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-02-01
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| Series: | Infection and Drug Resistance |
| Subjects: | |
| Online Access: | https://www.dovepress.com/differentiation-of-intraspinal-tuberculosis-and-metastatic-cancer-usin-peer-reviewed-article-IDR |
| _version_ | 1811205696045187072 |
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| author | Li Q Song J Li X Luo T Peng J Lv F Li Y Huang Z Wang A |
| author_facet | Li Q Song J Li X Luo T Peng J Lv F Li Y Huang Z Wang A |
| author_sort | Li Q |
| collection | DOAJ |
| description | QuanJiang Li,1,* Juan Song,2,* XinYou Li,1 TianYou Luo,1 Juan Peng,1 FaJin Lv,1 YongMei Li,1 ZhongXin Huang,1 AnRan Wang1 1Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China; 2Department of Gastroenterology & Endocrinology, Wuhan No. 9 Hospital, Wuhan, People’s Republic of China *These authors contributed equally to this workCorrespondence: Juan PengDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuanjiagang, Yuzhong District, Chongqing 400016, People’s Republic of ChinaTel +86 1 898 328 0171Email pengjuan0717@sina.comPurpose: This study aimed to explore the differences in the magnetic resonance imaging (MRI) findings between intraspinal tuberculosis and metastatic cancer, which may aid in making the correct diagnosis.Patients and Methods: The clinical features and MRI findings of 15 patients with intraspinal tuberculosis and 11 patients with intraspinal metastatic cancers were retrospectively analyzed.Results: The mean ages of the patients with intraspinal tuberculosis and metastatic cancer were 26.3 (15– 42) and 52.1 (38– 67) years, respectively. All intraspinal tuberculosis cases were secondary to primary extraspinal tuberculosis, including tuberculous meningitis (11/15), as well as pulmonary (9/15), vertebral (5/15), urinary tract (1/15), abdominal (1/15), cervical lymph node (1/15), and multisystem tuberculosis (9/15). The intraspinal metastases originated from the breast (5/11), lung (3/11), kidney (1/11), ovarian (1/11), and nasopharyngeal cancers (1/11). Both intraspinal tuberculosis and metastatic cancers presented with multiple intra- and extramedullary lesions throughout all regional segments of the spinal canal, accompanied by irregularly thickened meninges. Intraspinal tuberculous lesions had indistinct edges that integrated with each other, most of them exhibiting obvious enhancement on MRI. Conversely, intraspinal metastatic lesions were distinctly separated with clear edges and exhibited lesser enhanced MRI than intraspinal tuberculosis.Conclusion: A combined analysis of clinical features and MRI findings may be helpful in differentiating intraspinal tuberculosis from metastatic cancer.Keywords: intraspinal tuberculosis, intraspinal metastatic cancer, intramedullary nodule, leptomeningitis |
| first_indexed | 2024-04-12T03:35:16Z |
| format | Article |
| id | doaj.art-2fd34db85899456b8006d29fe2b2f602 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-04-12T03:35:16Z |
| publishDate | 2020-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-2fd34db85899456b8006d29fe2b2f6022022-12-22T03:49:26ZengDove Medical PressInfection and Drug Resistance1178-69732020-02-01Volume 1334134951569Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance ImagingLi QSong JLi XLuo TPeng JLv FLi YHuang ZWang AQuanJiang Li,1,* Juan Song,2,* XinYou Li,1 TianYou Luo,1 Juan Peng,1 FaJin Lv,1 YongMei Li,1 ZhongXin Huang,1 AnRan Wang1 1Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China; 2Department of Gastroenterology & Endocrinology, Wuhan No. 9 Hospital, Wuhan, People’s Republic of China *These authors contributed equally to this workCorrespondence: Juan PengDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuanjiagang, Yuzhong District, Chongqing 400016, People’s Republic of ChinaTel +86 1 898 328 0171Email pengjuan0717@sina.comPurpose: This study aimed to explore the differences in the magnetic resonance imaging (MRI) findings between intraspinal tuberculosis and metastatic cancer, which may aid in making the correct diagnosis.Patients and Methods: The clinical features and MRI findings of 15 patients with intraspinal tuberculosis and 11 patients with intraspinal metastatic cancers were retrospectively analyzed.Results: The mean ages of the patients with intraspinal tuberculosis and metastatic cancer were 26.3 (15– 42) and 52.1 (38– 67) years, respectively. All intraspinal tuberculosis cases were secondary to primary extraspinal tuberculosis, including tuberculous meningitis (11/15), as well as pulmonary (9/15), vertebral (5/15), urinary tract (1/15), abdominal (1/15), cervical lymph node (1/15), and multisystem tuberculosis (9/15). The intraspinal metastases originated from the breast (5/11), lung (3/11), kidney (1/11), ovarian (1/11), and nasopharyngeal cancers (1/11). Both intraspinal tuberculosis and metastatic cancers presented with multiple intra- and extramedullary lesions throughout all regional segments of the spinal canal, accompanied by irregularly thickened meninges. Intraspinal tuberculous lesions had indistinct edges that integrated with each other, most of them exhibiting obvious enhancement on MRI. Conversely, intraspinal metastatic lesions were distinctly separated with clear edges and exhibited lesser enhanced MRI than intraspinal tuberculosis.Conclusion: A combined analysis of clinical features and MRI findings may be helpful in differentiating intraspinal tuberculosis from metastatic cancer.Keywords: intraspinal tuberculosis, intraspinal metastatic cancer, intramedullary nodule, leptomeningitishttps://www.dovepress.com/differentiation-of-intraspinal-tuberculosis-and-metastatic-cancer-usin-peer-reviewed-article-IDRintraspinal tuberculosisintraspinal metastatic cancerintramedullary noduleleptomeningitis |
| spellingShingle | Li Q Song J Li X Luo T Peng J Lv F Li Y Huang Z Wang A Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging Infection and Drug Resistance intraspinal tuberculosis intraspinal metastatic cancer intramedullary nodule leptomeningitis |
| title | Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging |
| title_full | Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging |
| title_fullStr | Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging |
| title_full_unstemmed | Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging |
| title_short | Differentiation of Intraspinal Tuberculosis and Metastatic Cancer Using Magnetic Resonance Imaging |
| title_sort | differentiation of intraspinal tuberculosis and metastatic cancer using magnetic resonance imaging |
| topic | intraspinal tuberculosis intraspinal metastatic cancer intramedullary nodule leptomeningitis |
| url | https://www.dovepress.com/differentiation-of-intraspinal-tuberculosis-and-metastatic-cancer-usin-peer-reviewed-article-IDR |
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