The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex

The Structure of the Human Respiratory Syncytial Virus M2-1 Protein Bound to the Interaction Domain of the Phosphoprotein P Defines the Orientation of the Complex

ABSTRACT Human respiratory syncytial virus (HRSV) is a negative-stranded RNA virus that causes a globally prevalent respiratory infection, which can cause life-threatening illness, particularly in the young, elderly, and immunocompromised. HRSV multiplication depends on replication and transcription...

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Bibliographic Details
Main Authors: Muniyandi Selvaraj, Kavestri Yegambaram, Eleanor J. A. A. Todd, Charles-Adrien Richard, Rachel L. Dods, Georgia M. Pangratiou, Chi H. Trinh, Sophie L. Moul, James C. Murphy, Jamel Mankouri, Jean-François Éléouët, John N. Barr, Thomas A. Edwards
Format: Article
Language:English
Published: American Society for Microbiology 2018-12-01
Series:mBio
Subjects:
HRSV
M2-1
phosphoprotein
Online Access:https://journals.asm.org/doi/10.1128/mBio.01554-18

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