Immunoproteomic and Immunopeptidomic Analyses of Histoplasma capsulatum Reveal Promiscuous and Conserved Epitopes Among Fungi With Vaccine Potential

Immunoproteomic and Immunopeptidomic Analyses of Histoplasma capsulatum Reveal Promiscuous and Conserved Epitopes Among Fungi With Vaccine Potential

As there are more than 6 million human deaths due to mycoses each year, there is an urgent need to develop fungal vaccines. Moreover, given the similarities among pathogenic fungi, it may be possible to create a multi-fungi vaccine. In this study, we combined immunoproteomic and immunopeptidomic met...

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Bibliografiske detaljer
Main Authors: Brenda Kischkel, Camila Boniche-Alfaro, Isabela de Godoy Menezes, Suelen Andreia Rossi, Claudia Blanes Angeli, Sandro Rogério de Almeida, Giuseppe Palmisano, Leila Lopes-Bezerra, Joshua D. Nosanchuk, Carlos Pelleschi Taborda
Format: Article
Sprog:English
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Immunology
Fag:
vaccine
pan-fungal
peptide
dimorphic-fungi
proteomic
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2021.764501/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.764501/full

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