Effect of the isotiazole adjuvants in combination with cisplatin in chemotherapy of neuroepithelial tumors: experimental results and modeling

Abstract Chemotherapy is one of the main treatment options for cancer, but it is usually accompanied with negative side effects. The classical drugs combination with synergistic adjuvants can be the solution to this problem, allowing reducing therapeutic dose. Elucidating the mechanism of adjuvant a...

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Bibliographic Details
Main Authors: Vladimir Potkin, Aliaxandr Pushkarchuk, Alexandra Zamaro, Hongwei Zhou, Sergey Kilin, Sergey Petkevich, Irina Kolesnik, Dominik L. Michels, Dmitry A. Lyakhov, Vladimir A. Kulchitsky
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40094-9